CORDIS
EU research results

CORDIS

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Enhancing brown adipose tissue through NAD+ precursors: a new approach to treat cardiometabolic disease

Project information

Grant agreement ID: 840110

Status

Ongoing project

  • Start date

    1 June 2019

  • End date

    31 May 2021

Funded under:

H2020-EU.1.3.2.

  • Overall budget:

    € 175 572,48

  • EU contribution

    € 175 572,48

Coordinated by:

ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM

Netherlands

Project description

English EN

Fat cells recruited to fight cardiovascular disease

Hundreds of years ago, scientists discovered brown adipose tissue (BAT) in marmots. Since then, interest in BAT has waxed and waned. It was found in other mammals and even in new-born and infant children, and a metabolic role for BAT has solidified. Loaded with mitochondria, these specialised fat cells generate body heat, no shivering required. Discovery in adults a decade ago and a demonstrated role in insulin sensitivity have generated renewed interest in BAT as a therapeutic route to treatments for potentially fatal cardiometabolic disease. The eBAT project is studying a potentially very potent activator of BAT in cell lines and animal models, and as a dietary supplement.

Coordinator

ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM

Address

Meibergdreef 15
1105az Amsterdam

Netherlands

Activity type

Higher or Secondary Education Establishments

EU Contribution

€ 175 572,48

Project information

Grant agreement ID: 840110

Status

Ongoing project

  • Start date

    1 June 2019

  • End date

    31 May 2021

Funded under:

H2020-EU.1.3.2.

  • Overall budget:

    € 175 572,48

  • EU contribution

    € 175 572,48

Coordinated by:

ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM

Netherlands