CORDIS
EU research results

CORDIS

English EN

Genetic and lifestyle regulators of cardiometabolic risk in individuals gaining weight

Project information

Grant agreement ID: 846502

Status

Grant agreement signed

  • Start date

    1 September 2020

  • End date

    31 August 2022

Funded under:

H2020-EU.1.3.2.

  • Overall budget:

    € 207 312

  • EU contribution

    € 207 312

Coordinated by:

KOBENHAVNS UNIVERSITET

Denmark

Project description

English EN

Cardiometabolic risk factors in obesity

The increase in obesity rates in the human population worldwide is a major threat to public health systems. The main healthcare costs are due to cardiometabolic impairments such as insulin resistance, high cholesterol and hypertension, which increase the risk of type 2 diabetes and cardiovascular disease. Curiously, some obese individuals are resistant to cardiometabolic complications, while some normal weight individuals suffer from comorbidities usually linked to obesity. Recent genome studies have identified multiple genetic loci associated with increased subcutaneous and overall body fat deposition but lower cardiometabolic risks. The primary goal of the EU-funded GeneLifeCard project is to examine if genetic and lifestyle factors abolish the impact of long-term weight gain on cardiometabolic risk. The study will be carried out through meta-analyses (the statistical analysis combining results of multiple studies) of five different cohorts with repeated measures of body weight and cardiometabolic traits.

Leaflet | Map data © OpenStreetMap contributors, Credit: EC-GISCO, © EuroGeographics for the administrative boundaries

Coordinator

KOBENHAVNS UNIVERSITET

Address

Norregade 10
1165 Kobenhavn

Denmark

Activity type

Higher or Secondary Education Establishments

EU Contribution

€ 207 312

Project information

Grant agreement ID: 846502

Status

Grant agreement signed

  • Start date

    1 September 2020

  • End date

    31 August 2022

Funded under:

H2020-EU.1.3.2.

  • Overall budget:

    € 207 312

  • EU contribution

    € 207 312

Coordinated by:

KOBENHAVNS UNIVERSITET

Denmark