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Advancing a GMMA-based vaccine against invasive non-typhoidal salmonellosis through Phase 1 trial in Europe and sub-Saharan Africa

Project description

Bacteria engineered to produce vaccines for invasive non-typhoidal salmonellosis

Invasive non-typhoidal Salmonella (iNTS) disease is a major emerging public health concern, particularly in sub-Saharan Africa, where cases of fatality greatly exceed those due to typhoid fever. Commonly affecting infants, young children, and immuno-compromised adults, morbidity occurs in 20-25 % of cases. Vaccines are desperately needed here. The EU-funded Vacc-iNTS project has used a new methodology for vaccine production that is simple, low-cost and very effective at inducing an immune response in the body. They are going to test it in Phase 1 clinical trials and are already planning data collection to support Phase 2 and 3 activities.

Call for proposal

H2020-SC1-2018-Two-Stage-RTD
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Coordinator

SCLAVO VACCINES ASSOCIATION
Address
Piazza La Lizza 7
53100 Siena
Italy

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Activity type
Research Organisations
EU contribution
€ 1 152 311,51

Participants (11)

GSK VACCINES INSTITUTE FOR GLOBAL HEALTH SRL
Italy
EU contribution
€ 1 576 515
Address
Via Fiorentina 1
53100 Siena

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Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
United Kingdom
EU contribution
€ 2 227 288,92
Address
Wellington Square University Offices
OX1 2JD Oxford

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Activity type
Higher or Secondary Education Establishments
KENYA MEDICAL RESEARCH INSTITUTE
Kenya
EU contribution
€ 107 575,33
Address
Off Mbagathi Way
00200 Nairobi

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Activity type
Research Organisations
THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE
United Kingdom
EU contribution
€ 545 942,74
Address
Trinity Lane The Old Schools
CB2 1TN Cambridge

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Activity type
Higher or Secondary Education Establishments
UNIVERSITA DEGLI STUDI DI SIENA
Italy
EU contribution
€ 341 017,51
Address
Via Banchi Di Sotto 55
53100 Siena

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Activity type
Higher or Secondary Education Establishments
PRINS LEOPOLD INSTITUUT VOOR TROPISCHE GENEESKUNDE
Belgium
EU contribution
€ 31 296,56
Address
Nationalestraat 155
2000 Antwerpen

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Activity type
Higher or Secondary Education Establishments
THE UNIVERSITY OF LIVERPOOL
United Kingdom
EU contribution
€ 432 034,73
Address
Brownlow Hill 765 Foundation Building
L69 7ZX Liverpool

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Activity type
Higher or Secondary Education Establishments
UNIVERSITY OF OTAGO
New Zealand
EU contribution
€ 50 000
Address
Saint David Street
9054 Dunedin

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Activity type
Higher or Secondary Education Establishments
UNIVERSITE OUAGA I PROFESSEUR JOSEPH KI-ZERBO
Burkina Faso
EU contribution
€ 192 980,26
Address
.
03 Ouagadougou 03

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Activity type
Higher or Secondary Education Establishments
KWAME NKRUMAH UNIVERSITY OF SCIENCE AND TECHNOLOGY KUMASI
Ghana
EU contribution
€ 194 226,17
Address
Private Mail Bag, University Post Office
ASH Kumasi

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Activity type
Higher or Secondary Education Establishments
MMGH CONSULTING GMBH
Switzerland
EU contribution
€ 20 000
Address
Kuerbergstrasse 1
8049 Zurich

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Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)