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INnate-ImmunomeTabolIsm as Antiviral TargEt

INnate-ImmunomeTabolIsm as Antiviral TargEt

Objective

Viral outbreaks and epidemics continue to impose high morbidity and mortality burdens in mankind and animals, emphasizing the urgent need for the continuous improvement and innovation of our antiviral strategies. The innate immune system is pivotal for effective anti-viral defences. This field is now being revolutionised by the recognition that metabolic re-programming has a major impact on the host antiviral and inflammatory response to virus infections. The development of strategies targeted to these pathways represents an exciting new frontier for antiviral remedies. To drive this emerging field of antiviral immunometabolism and its application to viral diseases, INITIATE (INnate-ImmunomeTabolIsm as Antiviral TargEt) brings together a highly complementary team of world leaders, both academic and corporate, from the historically distinct research fields of virology, innate immunity and cellular metabolism in order to train a new generation of interdisciplinary scientists. Specifically, INITIATE will deliver training on the interrelationships between viral infection, host metabolism and immune defences through related and interdependent research projects, complemented with interdisciplinary and intersectoral secondments. Local and network-wide scientific workshops will be supplemented with transferrable skill workshops devoted to academia/industry collaboration, research dissemination and translation of knowledge into novel therapeutic interventions, public engagement and a successful research environment. INITIATE will result in a new generation of creative, entrepreneurial and innovative top-level interdisciplinary researchers, who will be at the forefront of the emerging research field of ‘antiviral immunometabolism’. These scientists will be able to face the inevitable future challenges in combating viral and other diseases, and they will be highly attractive to European Life Sciences industry and academia.
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Coordinator

ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM

Address

Dr Molewaterplein 40
3015 Gd Rotterdam

Netherlands

Activity type

Higher or Secondary Education Establishments

EU Contribution

€ 531 239,76

Participants (9)

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INSTITUTO PASTEUR ITALIA FONDAZIONECENCI BOLOGNETTI

Italy

EU Contribution

€ 522 999,36

THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN

Ireland

EU Contribution

€ 824 052,96

ACADEMISCH ZIEKENHUIS LEIDEN

Netherlands

EU Contribution

€ 531 239,76

CEMM - FORSCHUNGSZENTRUM FUER MOLEKULARE MEDIZIN GMBH

Austria

EU Contribution

€ 264 207,24

NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU

Norway

EU Contribution

€ 292 342,32

UNIVERSITEIT UTRECHT

Netherlands

EU Contribution

€ 265 619,88

STIMUNITY SAS

France

EU Contribution

€ 274 802,04

JANSSEN VACCINES & PREVENTION BV

Netherlands

EU Contribution

€ 265 619,88

ASTRAZENECA AB

Sweden

EU Contribution

€ 281 982,96

Partners (4)

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ELSEVIER BV

BIOCRATES LIFE SCIENCES AG

AGILENT TECHNOLOGIES SALES & SERVICES GMBH & CO KG

SOVALACC B.V.

Project information

Grant agreement ID: 813343

Status

Ongoing project

  • Start date

    1 May 2019

  • End date

    30 April 2023

Funded under:

H2020-EU.1.3.1.

  • Overall budget:

    € 4 054 106,16

  • EU contribution

    € 4 054 106,16

Coordinated by:

ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM

Netherlands