CORDIS
EU research results

CORDIS

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Mapping dEndritic inforMation prOcessing in behaving mice using simultaneous spatio-tempoRal voltage and calcium Imaging and wholE-cell electrophySiology

Project information

Grant agreement ID: 846215

Status

Ongoing project

  • Start date

    1 January 2020

  • End date

    31 December 2021

Funded under:

H2020-EU.1.3.2.

  • Overall budget:

    € 203 149,44

  • EU contribution

    € 203 149,44

Coordinated by:

ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE

Switzerland

Project description

English EN

Learning about memory formation with unprecedented imaging in behaving mice

Unlike most other cells in the body, neurons have a very special morphology critical to signal processing. A highly branched and dynamically changing 'dendritic tree' receives many inputs from other cells, opening ion channels and creating rapid changes in voltage for long-term modifications in structure and function related to learning and memory. Other voltage changes within the neurons may also modulate signals but observing these intracellular dynamics in awake and behaving animals was not possible until recently. MEMORIES has developed a pioneering technique and is planning to apply it for the first time ever to behaving mice. The experiments promise unprecedented insight into the neurobiological substrates of learning and memory.

Coordinator

ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE

Address

Batiment Ce 3316 Station 1
1015 Lausanne

Switzerland

Activity type

Higher or Secondary Education Establishments

EU Contribution

€ 203 149,44

Project information

Grant agreement ID: 846215

Status

Ongoing project

  • Start date

    1 January 2020

  • End date

    31 December 2021

Funded under:

H2020-EU.1.3.2.

  • Overall budget:

    € 203 149,44

  • EU contribution

    € 203 149,44

Coordinated by:

ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE

Switzerland