Project description
Novel in vitro biomimetic organs will speed nanoparticle testing
The 'eureka' moment is rarely a moment but rather the result of years of strategic experimentation. ActiTOX is developing in vitro biomimetic systems to speed up nanoparticle-based product testing for safety and toxicity while reducing the use of animal experimentation. The team is exploiting human-induced pluripotent stem cells (iPSCs), former adult somatic cells reprogrammed to their embryonic state. Scientists will reprogramme them to differentiate into cells in tissues of interest. The iPSCs will allow ActiTOX to bypass the ethical issues associated with embryonic stem cells while retaining the ability to create biomimetic organs of choice in culture.
Field of science
- /medical and health sciences/medical biotechnology/cells technologies/stem cells
Call for proposal
H2020-MSCA-RISE-2018
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Funding Scheme
MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE)
Coordinator
80686 Munchen
Germany
Participants (9)
11000 Praha
1040 Wien
9026 Gyor
10827 Berlin
8010 Graz
2970 Hoersholm
3500 Krems An Der Donau
14220 Praha 4
4200-135 Porto