Novel in vitro biomimetic organs will speed nanoparticle testing
The 'eureka' moment is rarely a moment but rather the result of years of strategic experimentation. ActiTOX is developing in vitro biomimetic systems to speed up nanoparticle-based product testing for safety and toxicity while reducing the use of animal experimentation. The team is exploiting human-induced pluripotent stem cells (iPSCs), former adult somatic cells reprogrammed to their embryonic state. Scientists will reprogramme them to differentiate into cells in tissues of interest. The iPSCs will allow ActiTOX to bypass the ethical issues associated with embryonic stem cells while retaining the ability to create biomimetic organs of choice in culture.
Field of science
- /medical and health sciences/medical biotechnology/cells technologies/stem cells
Call for proposal
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Funding SchemeMSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE)
3500 Krems An Der Donau