Project description DEENESFRITPL Young researchers take antibiotic resistance personally Historically, drugs for infection and disease have been developed from tests in large populations of similar patients. Scientific advances, particularly in the field of genetics, have ushered in a new era of personalised medicine in which genes, proteins and even parts of proteins can be used to create targeted therapeutics. Personalised antibiotic therapy is an area where such methods can be used to increase the efficacy of antibiotic therapy while combating the dangerous rise of antibiotic-resistant strains of bacteria. TIPAT is training young researchers in the techniques required to strategically evaluate drug-pathogen-host interactions for effective personalised antibiotic therapy. A fresh look at what is becoming a common problem may be just what the doctor ordered. Show the project objective Hide the project objective Objective Antimicrobial resistance (AMR) is an increasing threat to effectively treat serious bacterial infections. To this end, tailoring antibiotic treatments to individual patients is urgently needed to maximize efficacy while minimizing the risk of promoting further resistance. To enable development of innovative personalized antibiotic treatment strategies, quantitative understanding of the interplay between drug, pathogen and host is crucial. The Training towards Innovative Personalized Antibiotic Therapy (TIPAT) network will train inter-disciplinary specialists optimally equipped with a skill set to address this challenge.TIPAT offers a cutting-edge training-by-research programme for 15 Early Stage Researchers (ESRs) who will investigate translation and integration of biological and pharmacological data related to drug-pathogen-host interactions towards personalized therapies. Central to the TIPAT research and training program is the combination of state-of-the art quantitative modelling with approaches in clinical pharmacology, immunology and microbiology, which enables development of innovative methodology to personalized antibiotic therapies.The consortium unites a cross-disciplinary team of leading academic experts and inter-sectoral partners including SMEs, pharmaceutical companies and hospitals. Secondments complementary to ESR research projects will promote inter-professional and cross-disciplinary research and communication. The TIPAT integrated program is enriched with transferable, regulatory and entrepreneurial skills training delivered through themed Summer and Winter schools.The TIPAT network will deliver inter-disciplinary specialists in personalized antibiotic treatment strategies. The TIPAT training will strongly expand career perspectives of ESRs in academia, hospitals, industry or regulatory agencies, and develop scientific innovations to enable optimal therapy for individual patients to address current and future challenges of AMR-infections. Fields of science medical and health sciencesbasic medicineimmunologymedical and health sciencesbasic medicinepharmacology and pharmacypharmaceutical drugsantibioticsnatural sciencesbiological sciencesmicrobiologymedical and health sciencesbasic medicinepharmacology and pharmacydrug resistanceantibiotic resistance Programme(s) H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions Main Programme H2020-EU.1.3.1. - Fostering new skills by means of excellent initial training of researchers Topic(s) MSCA-ITN-2019 - Innovative Training Networks Call for proposal H2020-MSCA-ITN-2019 See other projects for this call Funding Scheme MSCA-ITN - Marie Skłodowska-Curie Innovative Training Networks (ITN) Coordinator UNIVERSITEIT LEIDEN Net EU contribution € 796 859,64 Address RAPENBURG 70 2311 EZ Leiden Netherlands See on map Region West-Nederland Zuid-Holland Agglomeratie Leiden en Bollenstreek Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 796 859,64 Participants (6) Sort alphabetically Sort by Net EU contribution Expand all Collapse all UPPSALA UNIVERSITET Sweden Net EU contribution € 845 948,88 Address VON KRAEMERS ALLE 4 751 05 Uppsala See on map Region Östra Sverige Östra Mellansverige Uppsala län Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 845 948,88 MEDIZINISCHE UNIVERSITAET WIEN Austria Net EU contribution € 792 621,72 Address SPITALGASSE 23 1090 Wien See on map Region Ostösterreich Wien Wien Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 792 621,72 UNIVERSITA DEGLI STUDI DI UDINE Participation ended Italy Net EU contribution € 0,00 Address VIA PALLADIO 8 33100 Udine See on map Region Nord-Est Friuli-Venezia Giulia Udine Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost No data BUNDESINSTITUT FUR IMPFSTOFFE UND BIOMEDIZINISCHE ARZNEIMITTEL Germany Net EU contribution € 505 576,80 Address PAUL-EHRLICH-STRASSE 51-59 63225 Langen See on map Region Hessen Darmstadt Offenbach, Landkreis Activity type Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 505 576,80 UNIVERSITATSKLINIKUM JENA Germany Net EU contribution € 505 576,80 Address KASTANIENSTR.1 07747 Jena See on map Region Thüringen Thüringen Jena, Kreisfreie Stadt Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 505 576,80 ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA Italy Net EU contribution € 522 999,36 Address VIA ZAMBONI 33 40126 Bologna See on map Region Nord-Est Emilia-Romagna Bologna Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 522 999,36