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Prepolarized MRI at Earth Field to seek new contrasts linked to molecular events for very early detection of pathologies

Project description

Imaging the activity of enzymes associated with disease will facilitate earlier diagnoses

Magnetic resonance imaging (MRI) is a non-invasive technology that generates high-resolution images of tissues and organs. Since its first use on a human being over 40 years ago, it has become instrumental in the diagnosis and monitoring of disease and injury. Functional MRI, invented in 1991, is based on the same principles but images metabolic activity indirectly via changes in blood flow. Its use has led to remarkable discoveries in biomedical research. Now, PRIMOGAIA is exploiting MRI technology to map and quantify enzyme activity in pathological tissue. Enzymes play critical roles in cellular metabolism and are already valuable biomarkers of pathology in blood tests. Now, their high-resolution spatial localisation in tissues will significantly enhance disease detection and monitoring.

Call for proposal

H2020-FETOPEN-2018-2020

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Sub call

H2020-FETOPEN-2018-2019-2020-01

Coordinator

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
Net EU contribution
€ 693 924,55
Address
Rue Michel Ange 3
75794 Paris
France

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Region
Ile-de-France Ile-de-France Paris
Activity type
Research Organisations
Non-EU contribution
€ 0,08

Participants (7)

Third-party

Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.

UNIVERSITE DE BORDEAUX
France
Net EU contribution
€ 33 959,20
Address
Place Pey Berland 35
33000 Bordeaux

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Region
Nouvelle-Aquitaine Aquitaine Gironde
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
FRAUNHOFER GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG EV
Germany
Net EU contribution
€ 447 000,00
Address
Hansastrasse 27c
80686 Munchen

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Region
Bayern Oberbayern München, Kreisfreie Stadt
Activity type
Research Organisations
Non-EU contribution
€ 0,00
PURE DEVICES GMBH
Germany
Net EU contribution
€ 440 400,00
Address
Kettelerstrasse 5-11
97222 Rimpar

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Bayern Unterfranken Würzburg, Landkreis
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
STELAR SRL
Italy
Net EU contribution
€ 417 500,00
Address
Via Enrico Fermi 4
27035 Mede

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Nord-Ovest Lombardia Pavia
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
UNIVERSITE DE MONS
Belgium
Net EU contribution
€ 475 750,00
Address
Place Du Parc 20
7000 Mons

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Region
Région wallonne Prov. Hainaut Arr. Mons
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
UNIVERSITA DEGLI STUDI DI TORINO
Italy
Net EU contribution
€ 444 466,25
Address
Via Giuseppe Verdi 8
10124 Torino

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Region
Nord-Ovest Piemonte Torino
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
UNIVERSITE D'AIX MARSEILLE
France
Net EU contribution
€ 434 821,25
Address
Boulevard Charles Livon 58 Le Pharo
13284 Marseille

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Region
Provence-Alpes-Côte d’Azur Provence-Alpes-Côte d’Azur Bouches-du-Rhône
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00