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Non-biased fluorescent dyes as markers of drugs for optical in cellulo and in vivo imaging

Project description

Novel fluorescent drug markers for in vivo imaging

Preclinical and clinical phases in drug discovery would greatly benefit from accurate information about drug distribution. In terms of safety, fluorescent imaging is much better than radioactive markers used in positron emission tomography. However, current fluorescent markers are large entities with positive or negative charge that could change drug properties. This EU-funded project involves four academic and two industrial interdisciplinary teams that aim to develop non-biased red and near infrared fluorescent dyes for in vivo imaging that do not affect the properties of labelled drugs. Developed dyes will be tested using representative known drugs for monitoring and analysis of their distribution in vitro and in vivo.

Call for proposal

H2020-MSCA-RISE-2019
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Coordinator

FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN-NUERNBERG
Address
Schlossplatz 4
91054 Erlangen
Germany
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 133 400

Participants (4)

CONSIGLIO NAZIONALE DELLE RICERCHE
Italy
EU contribution
€ 92 000
Address
Piazzale Aldo Moro 7
00185 Roma
Activity type
Research Organisations
INSTITUTUL DE CHIMIE MACROMOLECULARA PETRU PONI
Romania
EU contribution
€ 142 600
Address
Aleea Grigore Ghica Voda 41A
700487 Iasi
Activity type
Research Organisations
LIMITED LIABILITY SCIENTIFIC SERVICE COMPANY OTAVA
Ukraine
EU contribution
€ 230 000
Address
Borshagivska 117/125 Office 79
03056 Kyiv
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
NAUKOVO VYROBNICHYJ KOOPERATYV LECTINOTEST
Ukraine
EU contribution
€ 73 600
Address
Mechanichna 2
79024 Lviv
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)

Partners (1)

THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
United States
Address
Franklin Street 1111, 12 Floor
94607 Oakland Ca
Activity type
Higher or Secondary Education Establishments