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HCA|Organoid: Pilot action to establish a multi-tissue human organoid platform within the Human Cell Atlas as a booster of future disease-centric, mechanistic, and translational research

Project description

Human tissue organoid platform within the Human Cell Atlas initiative

The Human Cell Atlas project is a global scientific initiative with the goal to map and characterise all cells in the human body by types, numbers, locations, relationships and molecular structure. It is considered a fundamental future resource for scientists, enabling understanding of how healthy cells work and what happens in the case of a disease. The EU-funded HCA Organoid project will create a Human Organoid Atlas within the Human Cell Atlas initiative with the goal to deepen an ability to draw functional/causal/mechanistic conclusions relevant to human diseases. The project will establish single-cell transcriptomes, single-cell epigenomes and imaging data for several thousand organoids and matched primary tissue. Initially, focus will be on the colon and the brain with additional organs included as pilot studies. In general, this resource will enable characterisation of normal population variations and provide a baseline for disease studies.

Call for proposal

H2020-SC1-2019-Single-Stage-RTD
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Funding Scheme

RIA - Research and Innovation action

Coordinator

CEMM - FORSCHUNGSZENTRUM FUER MOLEKULARE MEDIZIN GMBH
Address
Lazarettgasse 14 Akh Bt 25.3
1090 Wien
Austria
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
EU contribution
€ 1 111 597,50

Participants (7)

INSTITUT FUER MOLEKULARE BIOTECHNOLOGIE GMBH
Austria
EU contribution
€ 610 748,75
Address
Dr Bohrgasse 3
1030 Wien
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
PRINSES MAXIMA CENTRUM VOOR KINDERONCOLOGIE BV
Netherlands
EU contribution
€ 923 125
Address
Heidelberglaan 25
3584CS Utrecht
Activity type
Other
STICHTING HUBRECHT ORGANOID TECHNOLOGY
Netherlands
EU contribution
€ 679 463,75
Address
Yalelaan 62
3584 CM Utrecht
Activity type
Other
FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION
Switzerland
EU contribution
€ 634 475
Address
Maulbeerstrasse 66
4058 Basel
Activity type
Research Organisations
DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG
Germany
EU contribution
€ 809 250
Address
Im Neuenheimer Feld 280
69120 Heidelberg
Activity type
Research Organisations
EUROPEAN MOLECULAR BIOLOGY LABORATORY
Germany
EU contribution
€ 69 777,50
Address
Meyerhofstrasse 1
69117 Heidelberg
Activity type
Research Organisations
EURICE EUROPEAN RESEARCH AND PROJECT OFFICE GMBH
Germany
EU contribution
€ 160 250
Address
Heinrich-hertz-allee 1
66386 St Ingbert
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)