Skip to main content

Shaping the Mechano-Pharmacological properties of Microparticles and Extracellular Vesicles for the Treatment of Osteoarthritis

Project description

Polymeric microparticles for the treatment of osteoarthritis

Osteoarthritis is the most common form of arthritis when the protective cartilage that cushions the ends of bones wears down over time, affecting millions of people worldwide. The disorder most commonly affects joints in hands, knees, hips and spine, and often leads to joint replacement surgery. Presently, the condition is not curable and only a symptomatic treatment is available. The EU-funded MEPHOS project aims to develop a novel integrated strategy for osteoarthritis treatment based on the intra-articular deposition of polymeric microplates providing simultaneous long-term pharmacological therapy and mechanical support. Polymeric microplates will provide continuous release of pain management medication and combination of molecules and biologicals, to prevent tissue degeneration while inducing regeneration processes. The project is a collaborative effort of seven European and American academic institutions and industrial partners for fabrication and biological and preclinical evaluation.

Leaflet | Map data © OpenStreetMap contributors, Credit: EC-GISCO, © EuroGeographics for the administrative boundaries

Coordinator

FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA
Net EU contribution
€ 312 800,00
Address
Via Morego 30
16163 Genova
Italy

See on map

Region
Nord-Ovest Liguria Genova
Activity type
Research Organisations
Non-EU contribution
€ 36 800,00

Participants (3)

UNIVERSIDAD DE NAVARRA
Spain
Net EU contribution
€ 253 000,00
Address
Campus Universitario Edificio Central
31080 Pamplona

See on map

Region
Noreste Comunidad Foral de Navarra Navarra
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 23 000,00
UNIVERSIDADE DO MINHO
Portugal
Net EU contribution
€ 225 400,00
Address
Largo Do Paco
4704 553 Braga

See on map

Region
Continente Norte Cávado
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 18 400,00
LIPOCURE LTD
Israel
Net EU contribution
€ 73 600,00
Address
Hadassah Ein Kerem Campus Building Jerusalem Biotechnology Park
91120 Jerusalem

See on map

SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 9 200,00

Partners (4)

Partner

Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.

BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
United States
Net EU contribution
€ 0,00
Address
Serra Mall 450
94305 2004 Stanford

See on map

Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 13 800,00
Partner

Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.

THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL
United States
Net EU contribution
€ 0,00
Address
"Airport Drive 104 Suite 2200 Cb #1350"
27599 Chapel Hill

See on map

Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 23 000,00
Partner

Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.

VANDERBILT UNIVERSITY
United States
Net EU contribution
€ 0,00
Address
West End Avenue 2201
37235 Nashville Tenessee

See on map

Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 27 600,00
Partner

Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.

University of Arkansas
United States
Net EU contribution
€ 0,00
Address
Ozark Hall, 1 University Of Arkansas 120
72701 Fayetteville

See on map

Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 23 000,00