Project description
Polymeric microparticles for the treatment of osteoarthritis
Osteoarthritis is the most common form of arthritis when the protective cartilage that cushions the ends of bones wears down over time, affecting millions of people worldwide. The disorder most commonly affects joints in hands, knees, hips and spine, and often leads to joint replacement surgery. Presently, the condition is not curable and only a symptomatic treatment is available. The EU-funded MEPHOS project aims to develop a novel integrated strategy for osteoarthritis treatment based on the intra-articular deposition of polymeric microplates providing simultaneous long-term pharmacological therapy and mechanical support. Polymeric microplates will provide continuous release of pain management medication and combination of molecules and biologicals, to prevent tissue degeneration while inducing regeneration processes. The project is a collaborative effort of seven European and American academic institutions and industrial partners for fabrication and biological and preclinical evaluation.
Fields of science
Programme(s)
Coordinator
16163 Genova
Italy
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Participants (3)
31080 Pamplona
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4704 553 Braga
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91120 Jerusalem
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
Partners (4)
Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
94305 2004 Stanford
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
27599 Chapel Hill
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
37235 Nashville Tenessee
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
72701 Fayetteville
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