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Automated Cellular Robot-Assisted Technologies for translation of discovery-led research in Osteoarthritis

Project description

Stem cell technology for the treatment of osteoarthritis

Osteoarthritis is a common type of arthritis associated with a breakdown of cartilage in joints. It is the most common chronic joint condition, affecting more than 40 million people in Europe alone. As there are limited treatment options available, osteoarthritis imposes a huge burden on healthcare systems. The goal of the EU-funded AutoCRAT project is to develop novel sustainable cell and cell-derived therapies for osteoarthritis. The project will use human-induced pluripotent stem cells for generation of articular chondrocytes for cartilage repair and human-induced mesenchymal stem cells for disease prevention and for the treatment of established disease. As an extended goal, the project will investigate potential application of the mesenchymal stem cell secretome as a next-generation therapy and will produce the therapeutics identified in the project using cost-effective robot-enabled processes in a novel manufacturing platform to expedite translation to patients.

Call for proposal

H2020-SC1-BHC-2018-2020

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Sub call

H2020-SC1-2019-Single-Stage-RTD

Coordinator

NATIONAL UNIVERSITY OF IRELAND GALWAY
Net EU contribution
€ 1 406 250,00
Address
University Road
H91 Galway
Ireland

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Region
Ireland Eastern and Midland Dublin
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00

Participants (8)

FRAUNHOFER GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG EV
Germany
Net EU contribution
€ 1 683 046,25
Address
Hansastrasse 27c
80686 Munchen

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Region
Bayern Oberbayern München, Kreisfreie Stadt
Activity type
Research Organisations
Other funding
€ 0,00
UNIVERSITA DEGLI STUDI DI GENOVA
Italy
Net EU contribution
€ 750 000,00
Address
Via Balbi 5
16126 Genova

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Region
Nord-Ovest Liguria Genova
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
ACADEMISCH ZIEKENHUIS LEIDEN
Netherlands
Net EU contribution
€ 1 006 181,25
Address
Albinusdreef 2
2333 ZA Leiden

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Region
West-Nederland Zuid-Holland Agglomeratie Leiden en Bollenstreek
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
GOETEBORGS UNIVERSITET
Sweden
Net EU contribution
€ 751 048,75
Address
Vasaparken
405 30 Goeteborg

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Region
Södra Sverige Västsverige Västra Götalands län
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
VALITACELL LTD
Ireland
Net EU contribution
€ 750 000,00
Address
Fosters Ave. - Mount Merrion, Blackrock
V94 Dublin 2

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Ireland Eastern and Midland Dublin
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
UNIVERSITAETSKLINIKUM ESSEN
Germany
Net EU contribution
€ 760 625,00
Address
Hufelandstrasse 55
45147 Essen

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Region
Nordrhein-Westfalen Düsseldorf Essen, Kreisfreie Stadt
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
PINTAIL LTD
Ireland
Net EU contribution
€ 199 993,75
Address
Springhill Avenue 77
A94 K542 Blackrock

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Ireland Eastern and Midland Dublin
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
PANAXEA BV
Netherlands
Net EU contribution
€ 145 625,00
Address
Science Park 400 Matrix Ii Unit 3.1
1098 XH Amsterdam

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
West-Nederland Noord-Holland Groot-Amsterdam
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00