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Host directed medicine in invasive fungal infection

Project description

Host-directed approach to cure invasive fungal infections

Invasive fungal infections (IFIs) represent a major threat in immunocompromised and critically ill adult and paediatric patients. Experts believe that a host-directed approach could help to improve the current situation. The EU-funded HDM-FUN project proposes a transdisciplinary approach to identify critical factors for host-directed medical interventions in IFIs. The overall objective is to identify host-pathogen factors essential for immunotherapy and prophylaxis, so as to enable the design of novel therapeutic and preventive host-directed medicine approaches for patients with lethal invasive fungal infection in intensive care. HDM-FUN brings together leading scientists and clinical researchers to study genetics and transcription host factors, metabolome and microbiome immune modulators and host pathogen interactions at molecular and cellular level that determine the susceptibility and treatment outcome of patients with fungal infection.

Call for proposal

H2020-SC1-2019-Two-Stage-RTD
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Coordinator

STICHTING RADBOUD UNIVERSITAIR MEDISCH CENTRUM
Address
Geert Grooteplein 10 Zuid
6525 GA Nijmegen
Netherlands
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 2 811 150

Participants (16)

INSTITUT PASTEUR
France
EU contribution
€ 692 185
Address
Rue Du Docteur Roux 25-28
75724 Paris Cedex 15
Activity type
Research Organisations
CENTRE HOSPITALIER UNIVERSITAIRE VAUDOIS
Switzerland
EU contribution
€ 703 000
Address
Rue Du Bugnon 21
1011 Lausanne
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
JOHANN WOLFGANG GOETHE-UNIVERSITAET FRANKFURT AM MAIN
Germany
EU contribution
€ 345 750
Address
Theodor W Adorno Platz 1
60323 Frankfurt Am Main
Activity type
Higher or Secondary Education Establishments
JULIUS-MAXIMILIANS-UNIVERSITAT WURZBURG
Germany
EU contribution
€ 319 950
Address
Sanderring 2
97070 Wuerzburg
Activity type
Higher or Secondary Education Establishments
UNIVERSIDADE DO MINHO
Portugal
EU contribution
€ 319 625
Address
Largo Do Paco
4704 553 Braga
Activity type
Higher or Secondary Education Establishments
UNIVERSITA DEGLI STUDI DI PERUGIA
Italy
EU contribution
€ 322 450
Address
Piazza Dell Universita 1
06123 Perugia
Activity type
Higher or Secondary Education Establishments
IDRYMA TECHNOLOGIAS KAI EREVNAS
Greece
EU contribution
€ 319 750
Address
N Plastira Str 100
70013 Irakleio
Activity type
Research Organisations
LEIBNIZ-INSTITUT FUR NATURSTOFF-FORSCHUNG UND INFEKTIONSBIOLOGIE EV HANS-KNOLL-ISTITUT
Germany
EU contribution
€ 319 700
Address
Beutenberg Strasse 11A
07745 Jena
Activity type
Research Organisations
UNIVERSITATEA DE MEDICINA SI FARMACIE IULIU HATIEGANU CLUJ-NAPOCA
Romania
EU contribution
€ 276 600
Address
Victor Babes Street 8
400012 Cluj-napoca
Activity type
Higher or Secondary Education Establishments
THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN
United Kingdom
EU contribution
€ 320 010
Address
King's College Regent Walk
AB24 3FX Aberdeen
Activity type
Higher or Secondary Education Establishments
DUKE UNIVERSITY
United States
EU contribution
€ 592 750
Address
Allen Building 207
27708 Durham Nc
Activity type
Higher or Secondary Education Establishments
KATHOLIEKE UNIVERSITEIT LEUVEN
Belgium
EU contribution
€ 684 000
Address
Oude Markt 13
3000 Leuven
Activity type
Higher or Secondary Education Establishments
Hycult biotechnology bv
Netherlands
EU contribution
€ 400 000
Address
Frontstraat 2A
5405 PB Uden
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
IMAGINE INSTITUT DES MALADIES GENETIQUES NECKER ENFANTS MALADES FONDATION
France
EU contribution
€ 1 220 750
Address
24 Bd Du Montparnasse
75015 Paris 15
Activity type
Research Organisations
INNOVATION ACTA S.R.L.
Italy
EU contribution
€ 350 500
Address
Via D.a. Azuni, 9
00196 Roma
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
STICHTING RADBOUD UNIVERSITEIT

Participation ended

Netherlands
EU contribution
€ 0
Address
Houtlaan 4
6525 XZ Nijmegen
Activity type
Higher or Secondary Education Establishments