Gut microbiome for tackling HIV infection
Although the microbiome has been the subject of intense research over recent decades, very few publications have addressed its potential role in HIV/AIDS - and most of these have focused on the genital microbiome. Increasing evidence supports a role for the gut microbiome in immune system disorders, chronic inflammation and accelerated ageing, all hallmarks of HIV-1 infection. The EU-funded MISTRAL project is exploring the gut microbiota in relation to HIV-1, seeking microbiome biomarkers to support development of interventions that mitigate infection and enhance response to vaccines and therapies. In addition, the creation of a publicly accessible database will aid inpatient screening and stratification. A cloud-based tool will also facilitate microbiome interpretation for reseach and clinical purposes.
Fields of science
Call for proposal
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Funding SchemeRIA - Research and Innovation action