Skip to main content

Microbiome-based stratification of individuals at risk of HIV-1 acquisition, chronic clinical complications,antimicrobial drug resistance,and unresponsiveness to therapeutic HIV-1 vaccination

Project description

Gut microbiome for tackling HIV infection

Although the microbiome has been the subject of intense research over recent decades, very few publications have addressed its potential role in HIV/AIDS - and most of these have focused on the genital microbiome. Increasing evidence supports a role for the gut microbiome in immune system disorders, chronic inflammation and accelerated ageing, all hallmarks of HIV-1 infection. The EU-funded MISTRAL project is exploring the gut microbiota in relation to HIV-1, seeking microbiome biomarkers to support development of interventions that mitigate infection and enhance response to vaccines and therapies. In addition, the creation of a publicly accessible database will aid inpatient screening and stratification. A cloud-based tool will also facilitate microbiome interpretation for reseach and clinical purposes.

Call for proposal

H2020-SC1-2019-Two-Stage-RTD
See other projects for this call

Funding Scheme

RIA - Research and Innovation action

Coordinator

FUNDACIO PRIVADA INSTITUT DE RECERCA DE LA SIDA-CAIXA
Address
Carretera De Canyet
08916 Barcelona
Spain
Activity type
Research Organisations
EU contribution
€ 3 967 500

Participants (10)

UNIVERSITE D'AIX MARSEILLE
France
EU contribution
€ 730 470
Address
Boulevard Charles Livon 58
13284 Marseille
Activity type
Higher or Secondary Education Establishments
REGION HOVEDSTADEN
Denmark
EU contribution
€ 1 017 611,25
Address
Kongens Vaenge 2
3400 Hillerod
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
CASE WESTERN RESERVE UNIVERSITY CORPORATION
United States
EU contribution
€ 727 787,50
Address
Euclid Avenue 10900
44106 7037 Cleveland Ohio
Activity type
Higher or Secondary Education Establishments
KAROLINSKA INSTITUTET
Sweden
EU contribution
€ 1 490 833,75
Address
Nobels Vag 5
17177 Stockholm
Activity type
Higher or Secondary Education Establishments
PROJECTE DELS NOMS - HISPANOSIDA ASOCIACION
Spain
EU contribution
€ 236 737,50
Address
Comte Borrell 164 166 Baixos
08015 Barcelona
Activity type
Other
CONSORCI INSTITUT D'INVESTIGACIONS BIOMEDIQUES AUGUST PI I SUNYER
Spain
EU contribution
€ 351 762,50
Address
Calle Rossello 149 Puerta Bjs
08036 Barcelona
Activity type
Other
FUNDACION PRIVADA INSTITUTO DE SALUD GLOBAL BARCELONA
Spain
EU contribution
€ 448 021,25
Address
C Rossello 132 Planta 05
08036 Barcelona
Activity type
Research Organisations
ASPHALION SL
Spain
EU contribution
€ 316 187,50
Address
Calle Tarragona, Numeros 151-157, Planta 10, Bloqu
08014 Barcelona
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
AELIX THERAPEUTICS SL
Spain
EU contribution
€ 534 978,75
Address
Calle Baldiri Reixac, 4-8
08028 Barcelona
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
VEDANTA BIOSCIENCES INC
United States
EU contribution
€ 172 493,75
Address
Corporation Trust Center 1209 Orange Street
19801 Wilmington
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)