CORDIS
EU research results

CORDIS

English EN

Microbiome-based stratification of individuals at risk of HIV-1 acquisition, chronic clinical complications,antimicrobial drug resistance,and unresponsiveness to therapeutic HIV-1 vaccination

Project information

Grant agreement ID: 847943

Status

Ongoing project

  • Start date

    1 January 2020

  • End date

    31 December 2024

Funded under:

H2020-EU.3.1.3.

  • Overall budget:

    € 9 994 383,75

  • EU contribution

    € 9 994 383,75

Coordinated by:

FUNDACIO PRIVADA INSTITUT DE RECERCA DE LA SIDA-CAIXA

Spain

Project description

English EN

Gut microbiome for tackling HIV infection

Although the microbiome has been the subject of intense research over recent decades, very few publications have addressed its potential role in HIV/AIDS - and most of these have focused on the genital microbiome. Increasing evidence supports a role for the gut microbiome in immune system disorders, chronic inflammation and accelerated ageing, all hallmarks of HIV-1 infection. The EU-funded MISTRAL project is exploring the gut microbiota in relation to HIV-1, seeking microbiome biomarkers to support development of interventions that mitigate infection and enhance response to vaccines and therapies. In addition, the creation of a publicly accessible database will aid inpatient screening and stratification. A cloud-based tool will also facilitate microbiome interpretation for reseach and clinical purposes.

Coordinator

FUNDACIO PRIVADA INSTITUT DE RECERCA DE LA SIDA-CAIXA

Address

Carretera De Canyet
08916 Barcelona

Spain

Activity type

Research Organisations

EU Contribution

€ 3 967 500

Participants (10)

UNIVERSITE D'AIX MARSEILLE

France

EU Contribution

€ 730 470

REGION HOVEDSTADEN

Denmark

EU Contribution

€ 1 017 611,25

CASE WESTERN RESERVE UNIVERSITY CORPORATION

United States

EU Contribution

€ 727 787,50

KAROLINSKA INSTITUTET

Sweden

EU Contribution

€ 1 490 833,75

PROJECTE DELS NOMS - HISPANOSIDA ASOCIACION

Spain

EU Contribution

€ 236 737,50

CONSORCI INSTITUT D'INVESTIGACIONS BIOMEDIQUES AUGUST PI I SUNYER

Spain

EU Contribution

€ 351 762,50

FUNDACION PRIVADA INSTITUTO DE SALUD GLOBAL BARCELONA

Spain

EU Contribution

€ 448 021,25

ASPHALION SL

Spain

EU Contribution

€ 316 187,50

AELIX THERAPEUTICS SL

Spain

EU Contribution

€ 534 978,75

VEDANTA BIOSCIENCES INC

United States

EU Contribution

€ 172 493,75

Project information

Grant agreement ID: 847943

Status

Ongoing project

  • Start date

    1 January 2020

  • End date

    31 December 2024

Funded under:

H2020-EU.3.1.3.

  • Overall budget:

    € 9 994 383,75

  • EU contribution

    € 9 994 383,75

Coordinated by:

FUNDACIO PRIVADA INSTITUT DE RECERCA DE LA SIDA-CAIXA

Spain