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Microbiome-based stratification of individuals at risk of HIV-1 acquisition, chronic clinical complications,antimicrobial drug resistance,and unresponsiveness to therapeutic HIV-1 vaccination

Project description

Gut microbiome for tackling HIV infection

Although the microbiome has been the subject of intense research over recent decades, very few publications have addressed its potential role in HIV/AIDS - and most of these have focused on the genital microbiome. Increasing evidence supports a role for the gut microbiome in immune system disorders, chronic inflammation and accelerated ageing, all hallmarks of HIV-1 infection. The EU-funded MISTRAL project is exploring the gut microbiota in relation to HIV-1, seeking microbiome biomarkers to support development of interventions that mitigate infection and enhance response to vaccines and therapies. In addition, the creation of a publicly accessible database will aid inpatient screening and stratification. A cloud-based tool will also facilitate microbiome interpretation for reseach and clinical purposes.

Call for proposal

H2020-SC1-BHC-2018-2020

See other projects for this call

Sub call

H2020-SC1-2019-Two-Stage-RTD

Coordinator

FUNDACIO PRIVADA INSTITUT DE RECERCA DE LA SIDA-CAIXA
Net EU contribution
€ 3 967 500,00
Address
Carretera De Canyet
08916 Barcelona
Spain
Activity type
Research Organisations
Non-EU contribution
€ 0,00

Participants (13)

UNIVERSITE D'AIX MARSEILLE
France
Net EU contribution
€ 692 345,00
Address
Boulevard Charles Livon 58 Le Pharo
13284 Marseille
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
Region
Provence-Alpes-Côte d’Azur Provence-Alpes-Côte d’Azur Bouches-du-Rhône
 
Third-party

Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.

MEDITERRANEE INFECTION
France
Net EU contribution
€ 38 125,00
Address
27 Bd Jean Moulin Faculte De Medeine Aile Rouge 3E
13005 Marseille
Activity type
Research Organisations
Non-EU contribution
€ 0,00
Region
Provence-Alpes-Côte d’Azur Provence-Alpes-Côte d’Azur Bouches-du-Rhône
 
REGION HOVEDSTADEN
Denmark
Net EU contribution
€ 1 017 611,25
Address
Kongens Vaenge 2
3400 Hillerod
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Non-EU contribution
€ 0,00
CASE WESTERN RESERVE UNIVERSITY CORPORATION
United States
Net EU contribution
€ 727 787,50
Address
Euclid Avenue 10900
44106 7037 Cleveland Ohio
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
KAROLINSKA INSTITUTET
Sweden
Net EU contribution
€ 1 490 833,75
Address
Nobels Vag 5
17177 Stockholm
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
PROJECTE DELS NOMS - HISPANOSIDA ASOCIACION
Spain
Net EU contribution
€ 236 737,50
Address
Comte Borrell 164 166 Baixos
08015 Barcelona
Activity type
Other
Non-EU contribution
€ 0,00
CONSORCI INSTITUT D'INVESTIGACIONS BIOMEDIQUES AUGUST PI I SUNYER
Spain
Net EU contribution
€ 255 512,50
Address
Calle Rossello 149 Puerta Bjs
08036 Barcelona
Activity type
Other
Non-EU contribution
€ 0,00
Third-party

Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.

HOSPITAL CLINIC DE BARCELONA
Spain
Net EU contribution
€ 96 250,00
Address
Calle Villarroel 170
08036 Barcelona
Activity type
Research Organisations
Non-EU contribution
€ 0,00
FUNDACION PRIVADA INSTITUTO DE SALUD GLOBAL BARCELONA
Spain
Net EU contribution
€ 418 883,75
Address
C Rossello 132 Planta 05
08036 Barcelona
Activity type
Research Organisations
Non-EU contribution
€ 0,00
Third-party

Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.

HOSPITAL CLINIC DE BARCELONA
Spain
Net EU contribution
€ 29 137,50
Address
Calle Villarroel 170
08036 Barcelona
Activity type
Research Organisations
Non-EU contribution
€ 0,00
ASPHALION SL
Spain
Net EU contribution
€ 316 187,50
SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Address
Calle Tarragona, Numeros 151-157, Planta 10, Bloqu
08014 Barcelona
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
AELIX THERAPEUTICS SL
Spain
Net EU contribution
€ 534 978,75
SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Address
Calle Baldiri Reixac, 4-8
08028 Barcelona
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
VEDANTA BIOSCIENCES INC
United States
Net EU contribution
€ 172 493,75
Address
Corporation Trust Center 1209 Orange Street
19801 Wilmington
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00