CORDIS
EU research results

CORDIS

English EN

A high-dimensional approach for unwinding immune-metabolic causes of cardiovascular disease-depression multimorbidities

Project information

Grant agreement ID: 848146

Status

Ongoing project

  • Start date

    1 January 2020

  • End date

    31 December 2024

Funded under:

H2020-EU.3.1.1.

  • Overall budget:

    € 5 990 515

  • EU contribution

    € 5 990 515

Coordinated by:

IDRYMA IATROVIOLOGIKON EREUNON AKADEMIAS ATHINON

Greece

Project description

English EN

Investigating mechanisms in CVD-depression comorbidity

Depression is highly associated with cardiovascular disease (CVD), significantly increasing the risk of CVD development, acute events and mortality, especially in women. As a consequence, it represents a social and economic issue affecting the patient’s life and causing healthcare costs to rise. However, the mechanisms and progression of the disease remain unknown. The EU-funded TO_AITION project works on the hypothesis that immune-metabolic dysregulation due to genetic, lifestyle and environmental risk factors affects immunity mechanisms leading to CVD-associated depression. The project will effectuate basic, preclinical and clinical research applying data-driven strategies to detect and describe immune-metabolic mechanisms responsible for CVD-depression comorbidity, aiming to improve diagnosis and management of the disease.

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Coordinator

IDRYMA IATROVIOLOGIKON EREUNON AKADEMIAS ATHINON

Address

Soranou Efesiou 4
115 27 Athina

Greece

Activity type

Research Organisations

EU Contribution

€ 879 343,75

Participants (13)

UNIVERSITEIT VAN AMSTERDAM

Netherlands

EU Contribution

€ 458 155

PIRKANMAA HOSPITAL DISTRICT

Finland

EU Contribution

€ 526 400

UNIVERSITAETSKLINIKUM BONN

Germany

EU Contribution

€ 440 000

PANEPISTIMIO IOANNINON

Greece

EU Contribution

€ 661 000

MICRONIT MICROTECHNOLOGIES BV

Netherlands

EU Contribution

€ 351 775

GENOWAY

France

EU Contribution

€ 249 921,25

RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG

Germany

EU Contribution

€ 330 000

STICHTING VUMC

Netherlands

EU Contribution

€ 429 682,50

UNIVERSYTET MEDYCZNY W LODZI.

Poland

EU Contribution

€ 252 000

UNIVERSITAIR MEDISCH CENTRUM UTRECHT

Netherlands

EU Contribution

€ 473 750

UNIVERSITE DE GENEVE

Switzerland

EU Contribution

€ 483 750

MARIOS LYMARAKIS KAI SIA EE

Greece

EU Contribution

€ 249 812,50

SOCIETE EUROPEENNE DE CARDIOLOGIE

France

EU Contribution

€ 204 925

Project information

Grant agreement ID: 848146

Status

Ongoing project

  • Start date

    1 January 2020

  • End date

    31 December 2024

Funded under:

H2020-EU.3.1.1.

  • Overall budget:

    € 5 990 515

  • EU contribution

    € 5 990 515

Coordinated by:

IDRYMA IATROVIOLOGIKON EREUNON AKADEMIAS ATHINON

Greece