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A high-dimensional approach for unwinding immune-metabolic causes of cardiovascular disease-depression multimorbidities

Project description

Investigating mechanisms in CVD-depression comorbidity

Depression is highly associated with cardiovascular disease (CVD), significantly increasing the risk of CVD development, acute events and mortality, especially in women. As a consequence, it represents a social and economic issue affecting the patient’s life and causing healthcare costs to rise. However, the mechanisms and progression of the disease remain unknown. The EU-funded TO_AITION project works on the hypothesis that immune-metabolic dysregulation due to genetic, lifestyle and environmental risk factors affects immunity mechanisms leading to CVD-associated depression. The project will effectuate basic, preclinical and clinical research applying data-driven strategies to detect and describe immune-metabolic mechanisms responsible for CVD-depression comorbidity, aiming to improve diagnosis and management of the disease.

Call for proposal

H2020-SC1-2019-Two-Stage-RTD
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Coordinator

IDRYMA IATROVIOLOGIKON EREUNON AKADEMIAS ATHINON
Address
Soranou Efesiou 4
115 27 Athina
Greece
Activity type
Research Organisations
EU contribution
€ 879 343,75

Participants (13)

UNIVERSITEIT VAN AMSTERDAM
Netherlands
EU contribution
€ 458 155
Address
Spui 21
1012WX Amsterdam
Activity type
Higher or Secondary Education Establishments
PIRKANMAA HOSPITAL DISTRICT
Finland
EU contribution
€ 526 400
Address
Teiskontie 35
33521 Tampere
Activity type
Research Organisations
UNIVERSITATSKLINIKUM BONN
Germany
EU contribution
€ 440 000
Address
Venusberg-campus 1
53127 Bonn
Activity type
Higher or Secondary Education Establishments
PANEPISTIMIO IOANNINON
Greece
EU contribution
€ 661 000
Address
Panepistemioypole Panepistemio Ioanninon
45110 Ioannina
Activity type
Higher or Secondary Education Establishments
MICRONIT HOLDING BV
Netherlands
EU contribution
€ 351 775
Address
Colosseum 15
7521 PV Enschede
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
GENOWAY
France
EU contribution
€ 249 921,25
Address
31 Rue Saint Jean De Dieu Technopark 2
69007 Lyon
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG
Germany
EU contribution
€ 330 000
Address
Seminarstrasse 2
69117 Heidelberg
Activity type
Higher or Secondary Education Establishments
STICHTING VUMC
Netherlands
EU contribution
€ 429 682,50
Address
De Boelelaan 1117
1081 HV Amsterdam
Activity type
Research Organisations
UNIVERSYTET MEDYCZNY W LODZI.
Poland
EU contribution
€ 252 000
Address
Al. Kosciuszki, 4
90419 Lodz
Activity type
Higher or Secondary Education Establishments
UNIVERSITAIR MEDISCH CENTRUM UTRECHT
Netherlands
EU contribution
€ 473 750
Address
Heidelberglaan 100
3584 CX Utrecht
Activity type
Higher or Secondary Education Establishments
UNIVERSITE DE GENEVE
Switzerland
EU contribution
€ 483 750
Address
Rue Du General Dufour 24
1211 Geneve
Activity type
Higher or Secondary Education Establishments
MARIOS LYMARAKIS KAI SIA EE
Greece
EU contribution
€ 249 812,50
Address
Ethnikis Antistaseos 132
15344 Gerakas Attiki
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
SOCIETE EUROPEENNE DE CARDIOLOGIE
France
EU contribution
€ 204 925
Address
Route Des Colles 2035
06903 Biot Sophia Antipolis
Activity type
Other