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EXposome Powered tools for healthy living in urbAN SEttings

Project information

Grant agreement ID: 874627

Status

Ongoing project

  • Start date

    1 January 2020

  • End date

    31 December 2024

Funded under:

H2020-EU.3.1.2.

  • Overall budget:

    € 11 993 907,03

  • EU contribution

    € 11 993 906,99

Coordinated by:

UNIVERSITEIT UTRECHT

Netherlands

Objective

By 2030 more than 80% of Europe’s population will live and interact with a complex urban environment, consisting of a mixture of social and environmental factors. These factors include: where we live and work, where and what we eat, our social network, and what chemical substances we are exposed to. Individually or collectively these factors, known as the Urban Exposome, have an often modifiable impact on our health and provide important targets to improve population health. By studying the impact of the Urban Exposome on the major contributors to Europe’s burden of disease: Cardio-Metabolic and Pulmonary Disease, EXPANSE will address one of the most pertinent questions for urban planners, policy makers, and European citizens: “How to maximize one’s health in a modern urban environment?”.
EXPANSE will take the next step in Exposome research by: 1) bringing together the Exposome and health data of more than 55 million Europeans in administrative cohorts, in-depth Exposome, phenotype, and OMICs information for more than 2 million Europeans, and personalized Exposome assessment for 5,000 individuals living in five “Urban Labs”; 2) applying a novel approach to use ultra-high-resolution mass-spectrometry to agnostically screen for exogenous chemicals in 10,000 blood samples; 3) studying the evolution of the Exposome and health through the life-course via both (matured) birth and adult cohorts; and 4) evaluating the impact of changes in the Urban Exposome on the burden of Cardio-Metabolic and Pulmonary Disease.
EXPANSE will translate its insights and innovations into research and dissemination tools that will be openly accessible via the EXPANSE toolbox. By applying innovative ethics-by-design throughout the project, the social and ethical acceptability of these tools will be safeguarded. Tool discoverability and accessibility will be stimulated through the EXPANSE hub in which citizens, public sector policy makers, and private sector companies collectively participate. EXPANSE is part of the European Human Exposome Network comprised of 9 projects selected from this same call

Coordinator

UNIVERSITEIT UTRECHT

Address

Heidelberglaan 8
3584 Cs Utrecht

Netherlands

Activity type

Higher or Secondary Education Establishments

EU Contribution

€ 2 073 925

Participants (19)

KAROLINSKA INSTITUTET

Sweden

EU Contribution

€ 677 356,84

HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH

Germany

EU Contribution

€ 559 591,29

SCHWEIZERISCHES TROPEN- UND PUBLIC HEALTH-INSTITUT

Switzerland

EU Contribution

€ 976 270,39

IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE

United Kingdom

EU Contribution

€ 937 385,78

UNIVERSITAIR MEDISCH CENTRUM UTRECHT

Netherlands

EU Contribution

€ 743 909,91

STICHTING VUMC

Netherlands

EU Contribution

€ 338 283,23

INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE

France

EU Contribution

€ 333 507,75

CENTRE INTERNATIONAL DE RECHERCHE SUR LE CANCER

France

EU Contribution

€ 1 266 093,43

TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

United States

EU Contribution

€ 687 259,89

ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI

United States

EU Contribution

€ 690 325,35

TARTU ULIKOOL

Estonia

EU Contribution

€ 546 305,15

INSTYTUT MEDYCYNY PRACY IMIENIA PROF. DRA MED. JERZEGO NOFERA W LODZI

Poland

EU Contribution

€ 219 630,06

FUNDACION PRIVADA INSTITUTO DE SALUD GLOBAL BARCELONA

Spain

EU Contribution

€ 566 223,29

AZIENDA SANITARIA LOCALE ROMA 1

Italy

EU Contribution

€ 277 861,58

ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON

Greece

EU Contribution

€ 427 195,24

Masarykova univerzita

Czechia

EU Contribution

€ 327 229,09

GAME SOLUTIONS LAB BV

Netherlands

EU Contribution

€ 127 744,93

M2M4ALL

Netherlands

EU Contribution

€ 142 808,79

UNIWERSYTET JAGIELLONSKI

Poland

EU Contribution

€ 75 000

Project information

Grant agreement ID: 874627

Status

Ongoing project

  • Start date

    1 January 2020

  • End date

    31 December 2024

Funded under:

H2020-EU.3.1.2.

  • Overall budget:

    € 11 993 907,03

  • EU contribution

    € 11 993 906,99

Coordinated by:

UNIVERSITEIT UTRECHT

Netherlands