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Computational biomechanics and bioengineering 3D printing to develop a personalized regenerative biological ventricular assist device to provide lasting functional support to damaged hearts

Project description

3D printing to restore a damaged heart

Ischemic heart disease (coronary artery disease) is the leading single cause of death in Europe. Biomedical researchers are seeking solutions in self-repairing mechanisms of tissues or organs. However, the most promising solution lies in advancements in cell reprogramming, biomaterials or 3D printing combined with the profound study of myocardial physiology. The EU-funded BRAV3 project will develop a lasting biological device able to pump alongside a damaged heart through the engineering of a regenerative tissue with the use of biomaterials, stem cells and advanced computational modelling with 3D printable designs. By developing biological ventricular assist devices (BioVADs), BRAV3 will bring a quantum leap in regenerative medicine and its translation towards the clinic, as well as impact the development of novel medical technologies whilst greatly advancing our knowledge on human heart development.

Call for proposal

H2020-SC1-BHC-2018-2020

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Sub call

H2020-SC1-2019-Single-Stage-RTD

Coordinator

UNIVERSIDAD DE NAVARRA
Net EU contribution
€ 800 500,00
Address
Campus Universitario Edificio Central
31080 Pamplona
Spain

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Region
Noreste Comunidad Foral de Navarra Navarra
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00

Participants (16)

TECHNISCHE UNIVERSITEIT EINDHOVEN
Netherlands
Net EU contribution
€ 490 000,00
Address
Groene Loper 3
5612 AE Eindhoven

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Region
Noord-Brabant Zuidoost-Noord-Brabant
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
KATHOLIEKE UNIVERSITEIT LEUVEN
Belgium
Net EU contribution
€ 555 250,00
Address
Oude Markt 13
3000 Leuven

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Region
Vlaams Gewest Prov. Vlaams-Brabant Arr. Leuven
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
UNIVERSITAETSKLINIKUM WUERZBURG - KLINIKUM DER BAYERISCHEN JULIUS-MAXIMILIANS-UNIVERSITAT
Germany
Net EU contribution
€ 683 125,00
Address
Josef-schneider-strasse 2
97080 Wurzburg

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Region
Bayern Unterfranken Würzburg, Kreisfreie Stadt
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
SERVICIO MADRILENO DE SALUD
Spain
Net EU contribution
€ 441 875,00
Address
Plaza Carlos Trias Bertran 7
28020 Madrid

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Region
Comunidad de Madrid Comunidad de Madrid Madrid
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Non-EU contribution
€ 0,00
UNIVERSITAIR MEDISCH CENTRUM UTRECHT
Netherlands
Net EU contribution
€ 740 000,00
Address
Heidelberglaan 100
3584 CX Utrecht

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Region
West-Nederland Utrecht Utrecht
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
FUNDACIO INSTITUT DE BIOENGINYERIA DE CATALUNYA
Spain
Net EU contribution
€ 740 000,00
Address
Carrer Baldiri Reixac Planta 2a 10-12
08028 Barcelona

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Region
Este Cataluña Barcelona
Activity type
Research Organisations
Non-EU contribution
€ 0,00
INSTITUTO DE BIOLOGIA EXPERIMENTAL E TECNOLOGICA
Portugal
Net EU contribution
€ 770 000,00
Address
Avenida Da Republica Quinta Do Marques
2781-901 Oeiras

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Continente Área Metropolitana de Lisboa Área Metropolitana de Lisboa
Activity type
Research Organisations
Non-EU contribution
€ 0,00
LEARTIKER, SCOOP
Spain
Net EU contribution
€ 579 375,00
Address
Av/ Xemein, 12
48270 Markina-xemein

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Noreste País Vasco Bizkaia
Activity type
Research Organisations
Non-EU contribution
€ 0,00
UNIVERSIDAD DE ZARAGOZA
Spain
Net EU contribution
€ 560 000,00
Address
Calle Pedro Cerbuna 12
50009 Zaragoza

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Region
Noreste Aragón Zaragoza
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
EBERS MEDICAL TECHNOLOGY SL
Spain
Net EU contribution
€ 559 375,00
Address
Avenida De Madrid 117 5 A
50010 Zaragoza

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Noreste Aragón Zaragoza
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
BOSTON SCIENTIFIC LIMITED
Ireland
Net EU contribution
€ 471 750,00
Address
Ballybrit Business Park
H91 Galway

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Region
Ireland Eastern and Midland Dublin
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
AE MEDICALIS BV
Netherlands
Net EU contribution
€ 150 000,00
Address
Industrieweg 78
5145 PW Waalwijk

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Noord-Brabant Midden-Noord-Brabant
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
PNO INNOVATION SL
Spain
Net EU contribution
€ 245 193,96
Address
Calle Gran De Gracia 1 Planta 2 Puerta 3
08012 Barcelona

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Region
Este Cataluña Barcelona
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
Third-party

Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.

PNO INNOVATION UNIPESSOAL LDA
Portugal
Net EU contribution
€ 114 687,50
Address
Avenida Da Republica 50
1069-211 Lisboa

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Region
Continente Área Metropolitana de Lisboa Área Metropolitana de Lisboa
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
Third-party

Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.

CIAOTECH Srl
Italy
Net EU contribution
€ 98 868,54
Address
Via Palestrina 25
00189 Roma

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Region
Centro (IT) Lazio Roma
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
VISCOFAN SA
Spain
Net EU contribution
€ 0,00
Address
Calle Berroas 15 4 Planta
31192 Aranguren

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Region
Noreste Comunidad Foral de Navarra Navarra
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00