Novel integrated serological surveillance of malaria and neglected tropical diseases
Malaria and neglected tropical diseases (NTDs) like lymphatic filariasis, onchocerciasis, trachoma and schistosomiasis affect 2 billion people yearly. Successfully targeting these diseases calls for integrated surveillance strategies. Malaria surveillance is routinely implemented through cross-sectional surveys; this provides as an opportunity to introduce serological testing by measuring antibodies to multiple pathogens in blood samples collected for malaria surveillance. The goal of the EU-funded MultiSeroSurv project is to characterise the sero-epidemiology of malaria and NTDs in longitudinal cohort studies in Ethiopia, Cambodia, Papua New Guinea and Senegal, measuring antibodies to 34 antigens from 12 pathogens in the single blood samples. The collected data will provide validation for the use of serology in detecting infections and determining how concurrent and past exposures to multiple parasites can be estimated through multiplex data analysis from cross-sectional surveys.
Fields of science
Funding SchemeERC-STG - Starting Grant
75724 Paris Cedex 15
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