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Algorithms and multiplex assays for integrated serological surveillance of malaria and neglected tropical diseases

Project description

Novel integrated serological surveillance of malaria and neglected tropical diseases

Malaria and neglected tropical diseases (NTDs) like lymphatic filariasis, onchocerciasis, trachoma and schistosomiasis affect 2 billion people yearly. Successfully targeting these diseases calls for integrated surveillance strategies. Malaria surveillance is routinely implemented through cross-sectional surveys; this provides as an opportunity to introduce serological testing by measuring antibodies to multiple pathogens in blood samples collected for malaria surveillance. The goal of the EU-funded MultiSeroSurv project is to characterise the sero-epidemiology of malaria and NTDs in longitudinal cohort studies in Ethiopia, Cambodia, Papua New Guinea and Senegal, measuring antibodies to 34 antigens from 12 pathogens in the single blood samples. The collected data will provide validation for the use of serology in detecting infections and determining how concurrent and past exposures to multiple parasites can be estimated through multiplex data analysis from cross-sectional surveys.

Host institution

INSTITUT PASTEUR
Net EU contribution
€ 1 174 500,00
Address
Rue Du Docteur Roux 25-28
75724 Paris Cedex 15
France

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Region
Ile-de-France Ile-de-France Paris
Activity type
Research Organisations
Other funding
€ 1 174 500,00

Beneficiaries (2)

INSTITUT PASTEUR
France
Net EU contribution
€ 1 174 500,00
Address
Rue Du Docteur Roux 25-28
75724 Paris Cedex 15

See on map

Region
Ile-de-France Ile-de-France Paris
Activity type
Research Organisations
Other funding
€ 1 174 500,00
INSTITUT PASTEUR DE DAKAR
Senegal
Net EU contribution
€ 325 500,00
Other funding
€ 325 500,00