Project description DEENESFRITPL Novel 3D image-processing technology locates VT ablation targets Patients at risk of ventricular tachycardia (VT) commonly undergo catheter ablation in the areas of myocardial scars responsible for arrhythmias. The initial phase of the intervention involves the intra-cardiac insertion of a mapping catheter which is invasive, often inaccurate and time-consuming. 3D cardiac imaging providing detailed structural information on ablation targets could overcome the shortcomings of this standard procedure. A recently developed novel 3D image-processing technology allows cardiologists to locate VT ablation targets and guide ablation procedures in a non-invasive, highly precise and rapid manner using widely available cardiac CT images. The EU-funded MAP-IN-HEART project will investigate the technical and economical feasibility of the innovative approach by assessing its efficacy and safety in a limited clinical study. Show the project objective Hide the project objective Objective Patients at risk of ventricular tachycardia (VT), the primary cause of sudden cardiac death, commonly undergo catheter ablation to cauterize the areas within myocardial scars responsible for arrythmias. However, the initial phase of the intervention devoted to identifying the ablation targets currently involves the intra-cardiac insertion of a mapping catheter characterized for being invasive, often inaccurate, and time-consuming. Pre-operative implementation of 3D cardiac imaging approaches to provide detailed structural information on ablation targets could overcome the shortcomings of standard catheter-based mapping. Still, state-of-the-art techniques have not lived up to their potential so far. During his ERC Starting Grant ECSTATIC (2017-2022), Prof. Hubert Cochet at University of Bordeaux developed a novel 3D image-processing technology (MAP-IN-HEART) which would allow cardiologists to locate VT ablation targets and guide ablation procedures in a non-invasive, highly precise and rapid manner using widely available cardiac CT images, without the need for a mapping catheter. In this ERC PoC project, we will investigate the technical feasibility of the innovative MAP-IN-HEART approach by assessing its efficiency and safety in a limited clinical study, and performing a cost-efficiency analysis. Moreover, we will ensure Freedom-To-Operate and explore all the potential paths for commercialization to finally develop a viable business strategy based on the technological aspects, the market needs and trends. Lastly, during this project we will gain technical and commercial proof-of-concept, providing the necessary information for potential commercialisation routes. Fields of science medical and health sciencesclinical medicinecardiologycardiovascular diseasescardiac arrhythmia Programme(s) H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC) Main Programme Topic(s) ERC-2019-POC - ERC Proof of Concept Grant Call for proposal ERC-2019-PoC See other projects for this call Funding Scheme ERC-POC - Proof of Concept Grant Coordinator UNIVERSITE DE BORDEAUX Net EU contribution € 69 500,00 Address Place pey berland 35 33000 Bordeaux France See on map Region Nouvelle-Aquitaine Aquitaine Gironde Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 Beneficiaries (2) Sort alphabetically Sort by Net EU contribution Expand all Collapse all UNIVERSITE DE BORDEAUX France Net EU contribution € 69 500,00 Address Place pey berland 35 33000 Bordeaux See on map Region Nouvelle-Aquitaine Aquitaine Gironde Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 Third-party Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure. CHU HOPITAUX DE BORDEAUX France Net EU contribution € 80 500,00 Address Rue dubernat 12 33404 Talence See on map Region Nouvelle-Aquitaine Aquitaine Gironde Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00
