Neural code and the electroencephalogram
The electroencephalogram (EEG) is an important non-invasive brain imaging tool in neuroscience and in the clinic. However, the neural circuit activity that gives rise to the EEG is poorly understood. The EU-funded ESNECO project puts forward an interdisciplinary approach combining theoretical modelling with multiscale neurophysiology and interventional techniques to develop mathematical tools to analyse the EEG and interpret it in terms of specific neural features. Such features are key elements of the microcircuit configuration and have been documented to contribute to brain disorders such as schizophrenia and autism spectrum disorders. The experiments will simultaneously record EEG and intracortical neural activity in mice to determine the contributions of specific classes of cells and specific patterns of activity in cells to different EEG features.
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