MethylRIDE: Charting DNA methylation reprogramming of Ice Age horses in the face of global climate change and extinction

Project description

The role of epigenetics in evolution

According to Charles Darwin's theory of evolution, organisms develop through the natural selection of small, inherited variations. However, recent evidence underscores the role of epigenetic changes in trait and medical phenotype determination, indicating that phenotype is not solely driven by our genome. The EU-funded MethylRIDE project aims to investigate how epigenetic changes affect the process of biological adaptation. For this purpose, scientists will focus their research on Ice Age horses, employing novel experimental and computational techniques to examine ancient DNA molecules preserved in paleontological material. Results will unveil the general role of epigenetics as a significant evolutionary force.

Field of science

• /natural sciences/biological sciences/genetics and heredity/genome
• /natural sciences/biological sciences/evolutionary biology
• /natural sciences/biological sciences/genetics and heredity/dna
• /natural sciences/biological sciences/genetics and heredity/epigenetics
• /natural sciences/earth and related environmental sciences/atmospheric sciences/climatology/climatic changes

Programme(s)

• H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility

Topic(s)

• MSCA-IF-2019 - Individual Fellowships

Call for proposal

H2020-MSCA-IF-2019
See other projects for this call

Funding Scheme

MSCA-IF-EF-ST - Standard EF

Coordinator

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS

Address

Rue Michel Ange 3
75794 Paris
France

Activity type

Research Organisations

EU contribution

€ 196 707,84