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From parental risk to child mental illness: a genetically informed investigation of intergenerational risk pathways

Project description

The aetiology of child psychiatric symptoms

Many mental disorders, such as depression and anxiety, may have their roots in early childhood. Half of mental illnesses are established before the age of 14. The EU-funded I-RISK project will pioneer a paradigm shift in intergenerational mental health research and provide unprecedented insights into the aetiology of child psychiatric symptoms. The project will identify causal intergenerational pathways linking parental risk factors to child psychiatric symptoms. It is the first study to apply cutting-edge genetically informed methods to identify intergenerational risk factors for child psychiatric symptoms. It will also consider the role of intermediate phenotypes, whether environmental (parenting) or biological (epigenetic and brain data). I-RISK will generate new genomic data and bring together four of the largest child cohorts in Europe.

Call for proposal

ERC-2019-COG
See other projects for this call

Funding Scheme

ERC-COG - Consolidator Grant

Host institution

UNIVERSITY COLLEGE LONDON
Address
Gower Street
WC1E 6BT London
United Kingdom
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 1 524 375

Beneficiaries (2)

UNIVERSITY COLLEGE LONDON
United Kingdom
EU contribution
€ 1 524 375
Address
Gower Street
WC1E 6BT London
Activity type
Higher or Secondary Education Establishments
ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM
Netherlands
EU contribution
€ 658 918
Address
Dr Molewaterplein 40
3015 GD Rotterdam
Activity type
Higher or Secondary Education Establishments