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Commercialization of 3D histopathological evaluation of osteoarthritis – new tools for therapy monitoring from preclinical testing to hospitals

Project description

A step change in the evaluation of bone histology with 3D micro-computerised tomography

Osteoarthritis is a debilitating chronic disease characterised by the degeneration of the slippery cushion between bones (cartilage), which normally enables nearly frictionless joint motion. When it wears down completely, the underlying bone begins to break down as well. The histological assessment of associated tissues is currently the gold standard for the evaluation of osteoarthritis, both in patients and in animal models of the disease. This conventionally involves preparing multiple thin slices of tissues on slides for evaluation with a light microscope. The EU-funded MUOTO project has developed a methodology to produce a 3D representation of a tissue sample based on computerised tomography (CT). The micro-CT procedure promises to enhance reliability and resolution while reducing time and cost. Moreover, it will accelerate the development of treatments and allow for earlier diagnosis, thus improving patient outcomes.

Host institution

OULUN YLIOPISTO
Net EU contribution
€ 150 000,00
Address
Pentti Kaiteran Katu 1
90014 Oulu
Finland

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Region
Manner-Suomi Pohjois- ja Itä-Suomi Pohjois-Pohjanmaa
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
No data

Beneficiaries (1)

OULUN YLIOPISTO
Finland
Net EU contribution
€ 150 000,00
Address
Pentti Kaiteran Katu 1
90014 Oulu

See on map

Region
Manner-Suomi Pohjois- ja Itä-Suomi Pohjois-Pohjanmaa
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
No data