Immunomodulatory metabolites in biomaterials
Biomaterials are crucial for the surgical correction of bone defects caused by diseases and traumatic fractures. Risks associated with this treatment include inflammation and bone infection, and the host immune response to implanted materials represents the main factor determining the long-term outcome of the treatment. Bioactive metabolites have emerged as one of the most innovative and potent approaches for immune response modulation. The incorporation of metabolites with immune regulatory properties is an especially attractive option for biomaterials, ensuring a site-specific delivery system and the modulation of the microenvironment. The goal of the EU-funded Met4Bone project is to develop novel biomaterials with incorporated metabolites as an effective strategy to modulate local immune response, leading to favourable outcomes of surgical bone remediation.
Call for proposal
See other projects for this call