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Exploring cell-to-cell heterogeneity and exploiting epigenetic regulation for the interception of myeloid disease cells.

Project description

Advancing cell-based interceptive medicine for blood cancers

Disease interception is a novel concept and refers to treating a disease before it fully manifests. However, the identification and specific targeting of diseased cells amongst a population of healthy cells without side effects remains a challenge. The EU-funded INTERCEPT-MDS project will establish a multidisciplinary training programme to offer early-stage researchers the necessary expertise in the field. From a scientific perspective, the project will focus on myeloid blood cancers and use single-cell state-of-the-art methodologies to develop novel research tools that can help identify clonally distinct cells. For targeting disease cells, the network will leverage European expertise in epigenetics and chromatin regulation. The project is expected to put the concept of disease interception to the test with the hope of improving clinical outcome for patients.

Coordinator

FUNDACIO INSTITUT DE RECERCA CONTRA LA LEUCEMIA JOSEP CARRERAS
Net EU contribution
€ 752 714,64
Address
Carretera De Can Ruti Cami De Les Escoles S/n
08916 Badalona
Spain

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Region
Este Cataluña Barcelona
Activity type
Research Organisations
Non-EU contribution
€ 0,00

Participants (9)

CHEMOTHERAPEUTISCHES FORSCHUNGSINSTITUT GEORG-SPEYER-HAUS STIFTUNG
Germany
Net EU contribution
€ 252 788,40
Address
Paul Ehrlich Strasse 42-44
60596 Frankfurt

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Region
Darmstadt Frankfurt am Main, Kreisfreie Stadt
Activity type
Research Organisations
Non-EU contribution
€ 0,00
VETERINAERMEDIZINISCHE UNIVERSITAET WIEN
Austria
Net EU contribution
€ 264 207,24
Address
Veterinaerplatz 1
1210 Vienna

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Region
Wien Wien
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM
Netherlands
Net EU contribution
€ 265 619,88
Address
Dr Molewaterplein 40
3015 GD Rotterdam

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Region
West-Nederland Zuid-Holland Groot-Rijnmond
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
MLL MUNCHNER LEUKAMIELABOR GMBH
Germany
Net EU contribution
€ 252 788,40
Address
Max Lebsche Platz 31
81377 Munchen

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Bayern Oberbayern München, Kreisfreie Stadt
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
UNIVERSITETET I BERGEN
Norway
Net EU contribution
€ 292 342,32
Address
Museplassen 1
5020 Bergen

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Region
Norge Vestlandet Vestland
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
BIOBAM BIOINFORMATICS SL
Spain
Net EU contribution
€ 250 904,88
Address
Avenida Peris Y Valero 78-23
46006 Valencia

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Este Comunitat Valenciana Valencia/València
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
KLINIKUM RECHTS DER ISAR DER TECHNISCHEN UNIVERSITAT MUNCHEN
Germany
Net EU contribution
€ 252 788,40
Address
Ismaninger Strasse 22
81675 Muenchen

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Region
Bayern Oberbayern München, Kreisfreie Stadt
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
UNIVERSITA DEGLI STUDI DI FIRENZE
Italy
Net EU contribution
€ 261 499,68
Address
Piazza San Marco 4
50121 Florence

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Region
Centro (IT) Toscana Firenze
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
France
Net EU contribution
€ 274 802,04
Address
Rue De Tolbiac 101
75654 Paris

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Region
Ile-de-France Ile-de-France Paris
Activity type
Research Organisations
Non-EU contribution
€ 0,00