Project description
From sequence to graph-based representations – a paradigm shift in genomics
Genome sequencing seeks to determine the order of As, Cs, Gs and Ts, representing the DNA nucleotides in the genome of an organism. Corresponding advances have led to steadily increasing amounts of data worldwide. Funded by the Marie Skłodowska-Curie programme, the ALPACA project will develop graph-based representations for genomes that build on combining individual variation in an evolutionarily meaningful way, thereby making it possible to process and analyse sequencing data more efficiently than traditional approaches, which are based on ordinary, sequence-type genome representations. The paradigm shift will play a critical role in personalised medicine and pathogen analysis.
Fields of science
Programme(s)
Coordinator
33615 Bielefeld
Germany
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Participants (12)
75794 Paris
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78153 Le Chesnay Cedex
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56126 Pisa
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20126 Milano
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3526 KV Utrecht
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40225 Dusseldorf
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69117 Heidelberg
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814 99 Bratislava
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00014 Helsingin Yliopisto
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75724 Paris Cedex 15
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CB2 1TN Cambridge
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841 04 Bratislava
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.