Non-viral gene therapy for intervertebral disc degeneration
Intervertebral disc (IVD) degeneration is a main cause of chronic low back pain and osteoarthritis of the joints, affecting many individuals worldwide. To restore tissue health in affected patients, the EU-funded CARTHAGO project is working on a non-viral gene therapy approach based on the delivery of oligonucleotides and encoding nucleic acids. This strategy combined with ultrasound overcomes accessibility issues of cartilaginous tissues encountered by traditional drugs and enhances tissue penetration and transfection. The work will be carried out by early-stage researchers who will also acquire transferable skills for a career in the field.
Fields of science
Call for proposal
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Funding SchemeMSCA-ITN-ETN - European Training Networks
NG7 1FD Nottingham
7522 NB Enschede