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A novel platform for the direct profiling of circulating cell-free ribonucleic acids in biofluids

Project description

New platform for an accurate diagnosis and staging of cancer with 'liquid biopsy'

Conventional cancer biopsies rely on invasive methods to take samples from a tumour's tissues. The sample is used for histological analysis for the clinical diagnosis, and for identification of prognostic and therapeutic targets. Circulating cell-free ribonucleic acids (ccfRNAs) have opened the door to a non-invasive alternative – liquid biopsy. However, despite extensive academic and clinical research, ccfRNAs have not yet entered the field of clinical diagnostics. This is in part because the current analytical methods are unsatisfactory, meaning that ccfRNA detection remains challenging, costly, and based on elaborate multi-step sample preparations. The EU-funded diaRNAgnosis project brings together a pan-European, multidisciplinary and intersectoral team to deliver a new platform for the direct quantitative measurement of ccfRNA signatures that are specifically and overexpressed in testicular germ cell tumour and prostate cancer.

Call for proposal

H2020-MSCA-RISE-2020
See other projects for this call

Funding Scheme

MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE)

Coordinator

DESTINA GENOMICA SLNE
Address
Avenida De La Innoaci0n 1 Edificio Bic
18100 Granada
Spain
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
EU contribution
€ 230 000

Participants (6)

OPTOELETTRONICA ITALIA SRL
Italy
EU contribution
€ 41 400
Address
Via Vienna 8
38121 Trento
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
UNIVERSITA DEGLI STUDI DI CATANIA
Italy
EU contribution
€ 110 400
Address
Piazza Universita 2
95131 Catania
Activity type
Higher or Secondary Education Establishments
UNIVERSITA DEGLI STUDI DI TRENTO
Italy
EU contribution
€ 124 200
Address
Via Calepina 14
38122 Trento
Activity type
Higher or Secondary Education Establishments
PRINSES MAXIMA CENTRUM VOOR KINDERONCOLOGIE BV
Netherlands
EU contribution
€ 124 200
Address
Heidelberglaan 25
3584CS Utrecht
Activity type
Other
UNIVERSIDAD DE GRANADA
Spain
EU contribution
€ 87 400
Address
Cuesta Del Hospicio Sn
18071 Granada
Activity type
Higher or Secondary Education Establishments
NANOGETIC SOCIEDAD LIMITADA
Spain
EU contribution
€ 41 400
Address
Calle Marques De Los Velez 2 6 C
18005 Granada
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)