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COVID-19 infections - Remote Early Detection

Objective

In this project, we will evaluate the use and performance of a CE-marked device (wearable), which uses sensors to measure breathing rate, pulse rate, skin temperature, and heart rate variability for the purpose of early detection and monitoring of COVID-19 in general and high-risk populations. At the same time, a mobile application will be used to track participant-reported symptoms. A prospective, observational study will follow 13,000 individuals from the general population and 7,000 high-risk individuals wearing the device and responding to participant self-report parameters via a purpose-designed app. Based on this data, an algorithm will indicate which individuals likely require general practitioner (GP) care (for COVID-19 diagnostic testing, further vital signs assessment, and/or treatment) and/or hospital care. To evaluate algorithm performance, the cohort will be tested for COVID-19 antibodies at the end of follow-up. COVID-19 seropositivity in the intervention cohort will be compared seropositivity in a control population of 20,000 individuals drawn from the same populations using the application only. Thus, this project will deliver a large body of information on COVID-19 PCR testing and antibodies that can be used to develop additional diagnostics and therapeutics in addition to validating remote vital signs and self-reported symptoms monitoring systems.

Call for proposal

H2020-JTI-IMI2-2020-21-single-stage
See other projects for this call

Funding Scheme

IMI2-RIA - Research and Innovation action

Coordinator

UNIVERSITAIR MEDISCH CENTRUM UTRECHT
Address
Heidelberglaan 100
3584 CX Utrecht
Netherlands
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 1 240 002,50

Participants (8)

AVA AG
Switzerland
EU contribution
€ 3 774 250
Address
Gutstrasse 73
8055 Zurich
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
JULIUS CLINICAL RESEARCH BV
Netherlands
EU contribution
€ 2 026 247,50
Address
Broederplein 41-43
3703 CD Zeist
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
UNIVERSITY COLLEGE LONDON
United Kingdom
EU contribution
€ 490 353,75
Address
Gower Street
WC1E 6BT London
Activity type
Higher or Secondary Education Establishments
VIVE - DET NATIONALE FORSKNINGS- OG ANALYSECENTER FOR VELFAERD
Denmark
EU contribution
€ 123 675
Address
Herluff Trolles Gade 11
1052 Copenhagen
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Stichting Sanquin Bloedvoorziening
Netherlands
EU contribution
€ 1 350 000
Address
Plesmanlaan 125
1006 AN Amsterdam
Activity type
Research Organisations
TAKEDA PHARMACEUTICALS INTERNATIONAL AG
Switzerland
EU contribution
€ 0
Address
Thurgauerstrasse 130
8152 Glattpark
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
ROCHE DIAGNOSTICS NEDERLAND BV
Netherlands
EU contribution
€ 0
Address
Transistorstraat 41
1322CK Almere
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
LABORMEDIZINOSCHES ZENTRUM DR RISCHOSTSCHWEIZ AG
Switzerland
EU contribution
€ 587 500
Address
Lagerstrasse 30
9470 Buchs
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)