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Unified computational solutions to disentangle biological interactions in multi-omics data

Project description

New framework to decipher biomolecular interaction

Attempts to improve animal and plant microbiome functions are largely unsuccessful since interactions between the host’s biological process and their microbiome remain only superficially understood. What is certain is that microbiome functions can be optimised for sustainable food production. The question is how. In this context, the EU-funded FindingPheno project will develop a holistic statistical framework to decipher biomolecular interactions between host and microbiome. Specifically, it will combine biological knowledge and state-of-the-art statistical methods: structural causal modelling, variable selection, dimensionality reduction and feature detection. The next step will be to apply the framework to case studies from actual food production systems. The aim is to demonstrate the utility of the framework and provide avenues for quick and easy application of this new approach.

Call for proposal

H2020-NMBP-TR-IND-2020-twostage
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Coordinator

KOBENHAVNS UNIVERSITET
Address
Norregade 10
1165 Kobenhavn
Denmark
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 1 854 905

Participants (7)

TURUN YLIOPISTO
Finland
EU contribution
€ 716 132,50
Address
Yliopistonmaki
20014 Turku
Activity type
Higher or Secondary Education Establishments
OKOLOGIAI KUTATOKOZPONT
Hungary
EU contribution
€ 612 562,50
Address
Karolina Ut 29
1113 Budapest
Activity type
Research Organisations
FUNDACAO D. ANNA SOMMER CHAMPALIMAUD E DR. CARLOS MONTEZ CHAMPALIMAUD
Portugal
EU contribution
€ 658 511,25
Address
Avenida Brasilia, Centro De Investigacao Da Fundacao Champalimaud
1400-038 Lisboa
Activity type
Research Organisations
EUROPEAN MOLECULAR BIOLOGY LABORATORY
Germany
EU contribution
€ 1 349 473,75
Address
Meyerhofstrasse 1
69117 Heidelberg
Activity type
Research Organisations
QIAGEN AARHUS AS
Denmark
EU contribution
€ 223 750
Address
Silkeborgvej 2
8000 Aarhus
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
CHR. HANSEN A/S
Denmark
EU contribution
€ 187 000
Address
Boege Alle 10-12
2970 Hoersholm
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
NJORTH BIO SCIENCE LIMITED
United Kingdom
EU contribution
€ 190 750
Address
Station Road Pem Salisbury House
CB1 2LA Cambridge
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)