Knowledge At the Tip of Your fingers: Clinical Knowledge for Humanity

Objective

AI-empowered Personalized Medicine promises to find tailored, targeted, nearly “hand-made” cures for patients. Cancer treatment desperately needs boosters to find tailored, targeted cures for patients and Personalized Medicine can play a crucial role. Tailored targeted therapies in cancer treatment are already a reality but the current practice of targeted therapies in cancer treatment has been derived with traditional methods of data analysis. AI-empowered Personalized Medicine may help to bring targeted therapies to the next level. However, no matter how precise it is, no matter how many lives it can save in principle, and no matter if it can utilize the entire medical knowledge. If clinicians do not understand its suggestions and decisions, AI-empowered Personalized Medicine will not be a game changer, clinicians will not use it to make everyday decisions and, thus, it is doomed to fail. Hence, the real challenge is building AI-empowered Personalized Medicine systems that can be accepted by clinicians and clinical researchers. In KATY, we grasp the above challenge and we propose an AI-empowered Personalized Medicine system that can bring medical “AI-empowered knowledge” to the tips of the fingers of clinicians and clinical researchers. The AI-empowered knowledge is a human interpretable knowledge that clinicians and clinical researchers can: understand, trust and effectively use in their everyday working routine. KATY is then a AI-empowered Personalized Medicine system built around two main components: A Distributed Knowledge Graph and A pool of eXplainable Artificial Intelligence predictors. As a stress test and due to the lack of personalized clinical responses, KATY will be experimented in a low prevalence and complex cancer: Clear cell renal cell carcinoma (ccRCC).

Fields of science

• natural sciences › computer and information sciences › data science › data analysis
• natural sciences › computer and information sciences › artificial intelligence
• medical and health sciences › clinical medicine › cancer

Programme(s)

• H2020-EU.3.1.5. - Methods and data

Topic(s)

• DT-TDS-04-2020 - AI for Genomics and Personalised Medicine

Call for proposal

H2020-SC1-FA-DTS-2020-1
See other projects for this call

Funding Scheme

RIA - Research and Innovation action

Coordinator

UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA

Address

Via Cracovia 50
00133 Roma
Italy

Activity type

Higher or Secondary Education Establishments

EU contribution

€ 1 329 687,50

Participants (19)

COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES

France

EU contribution

€ 729 141,25

Address

Rue Leblanc 25
75015 Paris 15

Activity type

Research Organisations

FCIENCIAS.ID - ASSOCIACAO PARA A INVESTIGACAO E DESENVOLVIMENTO DE CIENCIAS

Portugal

EU contribution

€ 587 420

Address

Campo Grande, Edificio C1, Piso 3
1749 016 Lisbon

Activity type

Research Organisations

THE UNIVERSITY OF EDINBURGH

United Kingdom

EU contribution

€ 780 715

Address

Old College, South Bridge
EH8 9YL Edinburgh

Activity type

Higher or Secondary Education Establishments

DS TECH SRL

Italy

EU contribution

€ 366 500

Address

Via Salaria 719
00138 Roma

Activity type

Private for-profit entities (excluding Higher or Secondary Education Establishments)

UNIWERSYTET GDANSKI

Poland

EU contribution

€ 649 781,25

Address

Ul. Bazynskiego 8
80309 Gdansk

Activity type

Higher or Secondary Education Establishments

THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS

United Kingdom

EU contribution

€ 409 952,50

Address

North Street 66 College Gate
KY16 9AJ St Andrews

Activity type

Higher or Secondary Education Establishments

UNIVERSITAT WIEN

Austria

EU contribution

€ 299 931,25

Address

Universitatsring 1
1010 Wien

Activity type

Higher or Secondary Education Establishments

FUNDACIO EURECAT

Spain

EU contribution

€ 483 750

Address

Avenida Universitat Autonoma 23
08290 Cerdanyola Del Valles (Barcelona)

Activity type

Research Organisations

EURICE EUROPEAN RESEARCH AND PROJECT OFFICE GMBH

Germany

EU contribution

€ 531 250

Address

Heinrich-hertz-allee 1
66386 St Ingbert

Activity type

Private for-profit entities (excluding Higher or Secondary Education Establishments)

OPEN EVIDENCE

Spain

EU contribution

€ 272 500

Address

Avingunda Tibidabo 39
08035 Barcelona

Activity type

Private for-profit entities (excluding Higher or Secondary Education Establishments)

FONDAZIONE IRCCS ISTITUTO NAZIONALE DEI TUMORI

Italy

EU contribution

€ 249 875

Address

Via Venezian 1
20133 Milan

Activity type

Research Organisations

LAB4LIFE SPOLKA Z OGRANICZONA ODPOWIEDZIALNOSCIA

Poland

EU contribution

€ 211 800

Address

Al. Zwyciestwa 96/98
81 451 Gdynia

Activity type

Private for-profit entities (excluding Higher or Secondary Education Establishments)

UNIVERSIDAD DE ZARAGOZA

Spain

EU contribution

€ 200 000

Address

Calle Pedro Cerbuna 12
50009 Zaragoza

Activity type

Higher or Secondary Education Establishments

PERSONAL GENOMICS SRL

Italy

EU contribution

€ 173 750

Address

Via Roveggia 43
37136 Verona

Activity type

Private for-profit entities (excluding Higher or Secondary Education Establishments)

CENTRE HOSPITALIER UNIVERSITAIRE DE GRENOBLE

France

EU contribution

€ 58 645

Address

Boulevard De La Chantourne
38700 La Tronche

Activity type

Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)

LUNDS UNIVERSITET

Sweden

EU contribution

€ 280 430

Address

Paradisgatan 5C
22100 Lund

Activity type

Higher or Secondary Education Establishments

INSTITOUTO POLITIKIS YGEIAS ASTIKI MI KERDOSKOPIKI ETAIREIA

Greece

EU contribution

€ 303 250

Address

Agisilaou 8
151 23 Marousi Attikis

Activity type

Other

ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON

Greece

EU contribution

€ 382 083,75

Address

6 Christou Lada Str
10561 Athina

Activity type

Higher or Secondary Education Establishments

NATIONAL TECHNICAL UNIVERSITY OF UKRAINE IGOR SIKORSKY KYIV POLYTECHNIC INSTITUTE

Ukraine

EU contribution

€ 179 437,50

Address

Prospect Peremohy 37
03056 Kyiv

Activity type

Higher or Secondary Education Establishments