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A patient-centered early risk prediction, prevention, and intervention platform to support the continuum of care in coronary artery disease (CAD) using eHealth and artificial intelligence

Objective

Coronary artery disease (CAD) remains the leading cause of disease burden globally. CAD develops slowly, usually over decades, and depends on multiple (often modifiable) risk factors and their interactions. Self-management and patient activation are of rising importance as current restrictions in healthcare budgets impose great difficulties to enable the provision of qualitative secondary prevention to all cardiac patients in an era facing a huge cardiovascular disease epidemic.
The main hypothesis in the patient-centered TIMELY pathway, is that a modular, collaborative eHealth platform, supported by Artificial Intelligence (AI) for the continuous and in-time prediction of cardiac risks and complications and the induction of targeted behavioural change interventions, can be effective and cost-efficient for the secondary prevention of CAD by limiting the physiological and psychological effects of the disease and improving risk factor and symptom management. Improvements in patients’ self-care and empowerment and clinicians’ efficiency are also expected.
Along the continuum of the disease, prediction of the individual risk for disease progression, including physical impairment and severe events, is mandatory for timely intervention. TIMELY is a platform that provides AI-powered apps and dashboards and decision support tools assisting patients and clinicians to personalize healthcare based on risk evaluation, outcome prediction and tailored interventions. The platform will be developed based on a functional platform for Interoperability with electronic health records and security mechanisms, to ensure information completeness and continuity and to simplify data sharing. AI in TIMELY, built with big retrospective datasets of >23.000 CAD patients, will constantly monitor and evaluate risks and will indicate any deviation from defined therapy goals or unfavorable changes as well as propose proper interventions.

Call for proposal

H2020-SC1-DTH-2020-1
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Funding Scheme

RIA - Research and Innovation action

Coordinator

UNIVERSITEIT VAN AMSTERDAM
Address
Spui 21
1012WX Amsterdam
Netherlands
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 800 000

Participants (12)

RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG
Germany
EU contribution
€ 337 500
Address
Seminarstrasse 2
69117 Heidelberg
Activity type
Higher or Secondary Education Establishments
BIOTRONIK VERTRIEBS GMBH & CO. KG
Germany
EU contribution
€ 215 000
Address
Woermannkehre 1
12359 Berlin
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
IDRYMA TECHNOLOGIAS KAI EREVNAS
Greece
EU contribution
€ 448 125
Address
N Plastira Str 100
70013 Irakleio
Activity type
Research Organisations
Private Universitaet Witten/Herdecke gGmbH
Germany
EU contribution
€ 715 625
Address
Alfred-herrhaussen Strasse 50
58455 Witten
Activity type
Higher or Secondary Education Establishments
STICHTING KATHOLIEKE UNIVERSITEIT BRABANT
Netherlands
EU contribution
€ 449 375
Address
Warandelaan 2
5037 AB Tilburg
Activity type
Higher or Secondary Education Establishments
IEM GMBH
Germany
EU contribution
€ 618 750
Address
Cockerillstrasse 69
52222 Stolberg
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
FUNDACION INSTITUTO DE INVESTIGACION MARQUES DE VALDECILLA
Spain
EU contribution
€ 233 750
Address
Avenida Cardenal Herrera Oria S N
39011 Santander
Activity type
Research Organisations
SERVIZO GALEGO DE SAUDE
Spain
EU contribution
€ 369 000
Address
Edificio Administrativo San Lázaro
15703 Santiago De Compostela
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
CAPEMED EE
Greece
EU contribution
€ 352 500
Address
Epistimoniko Texnologiko Parko Panepistimiou Ioann
45500 Ioannina
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
SEMDATEX GMBH
Germany
EU contribution
€ 713 750
Address
Wisbyer Strasse 16/17
10439 Berlin
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
TECHNISCHE UNIVERSITAET DRESDEN
Germany
EU contribution
€ 281 187,50
Address
Helmholtzstrasse 10
01069 Dresden
Activity type
Higher or Secondary Education Establishments
MEDIZINISCHE UNIVERSITAT GRAZ
Austria
EU contribution
€ 202 500
Address
Auenbruggerplatz 2
8036 Graz
Activity type
Higher or Secondary Education Establishments