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Health-benefit understanding of mercury-selenium interactions from fish to human

Objective

MERFISH brings together international experts from a wide array of interdisciplinary research areas (analytical chemistry, fish nutrition, environmental science, communication, toxicology & aquaculture) from industry and academia from EU, Brazil and Mauritius, with a long-term goal of furthering the understanding of the source, transport, fate and effects of mercury from fish to humans and the detoxification role of selenium. MERFISH surges from a global demand, directly related to mercury, one of the top ten chemicals of major public health concern identified by the World Health Organization. However, mercury metabolic pathways in biota still remain poorly understood. Its understanding is crucial to elucidate its (eco)toxic effect and to identify important drivers of the mercury biogeochemical cycle.
Fish and seafood consumption is the principal human exposure source to (toxic) methymercury. EU food safety authorities (such as EFSA), and well-known US and United Nation environmental and food organizations (such as USEPA and FAO) clearly advise about avoiding certain fish species for vulnerable populations (including pregnant women and young children) depending on their methymercury concentrations. Mercury binding with proteins has been identified as a potential cause for toxicity and the role of selenium as antagonist for mercury toxicity has been identified but not well understood. MERFISH is based on the development of novel analytical approaches to gather new knowledge about mercury and selenium mechanisms in fish and humans. The project will be a critical contribution to establishing more realistic scenarios to estimate human health risk and benefits, but also to better capture the economic impacts on commercial fisheries. MERSFISH will build a lasting research network to answer emerging challenges in analytical chemistry, food safety, trophic transfer, fish nutrition and environmental and human health related to the global mercury issue.

Call for proposal

H2020-MSCA-RISE-2020
See other projects for this call

Funding Scheme

MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE)

Coordinator

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
Address
Rue Michel Ange 3
75794 Paris
France
Activity type
Other
EU contribution
€ 82 800

Participants (7)

INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT
France
EU contribution
€ 9 200
Address
147 Rue De L'universite
75007 Paris Cedex 07
Activity type
Research Organisations
HAVFORSKNINGSINSTITUTTET
Norway
EU contribution
€ 46 000
Address
Nordnesgaten 50
5817 Bergen
Activity type
Research Organisations
INSTITUT JOZEF STEFAN
Slovenia
EU contribution
€ 69 000
Address
Jamova 39
1000 Ljubljana
Activity type
Research Organisations
ADVANCED ISOTOPIC ANALYSIS
France
EU contribution
€ 13 800
Address
2 Avenue Du President Pierre Angot Technopole Heli
64000 Pau
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
PS ANALYTICAL LIMITED
United Kingdom
EU contribution
€ 0
Address
Arthur House Crayfields Industrial
BR5 3HP Orpington
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
EUROPE FOR BUSINESS LTD
United Kingdom
EU contribution
€ 59 800
Address
520, Birchwood Boulevard Birchwood
WA3 7QX Warrington
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
UNIVERSIDAD COMPLUTENSE DE MADRID
Spain
EU contribution
€ 9 200
Address
Avenida De Seneca 2
28040 Madrid
Activity type
Higher or Secondary Education Establishments

Partners (2)

MARINE BIOTECHNOLOGY PRODUCTS LTD
Mauritius
Address
Motorway M2, Riche Terre
Port Louis
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
UNIVERSIDADE DE SAO PAULO
Brazil
Address
Rua Da Reitoria 109 Butanta
05508 900 Sao Paulo Sp
Activity type
Higher or Secondary Education Establishments