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Pathogen-responsive hydrogels release antimicrobial vesicles for local infection treatment

Project description

Antimicrobial vesicles-containing hydrogels for the treatment of infections

Bacterial resistance against antibiotics is quickly becoming the leading cause of morbidity and mortality worldwide. Effective, focused treatments of bacterial infections are required to prevent the formation of new resistances. The researchers of the EU-funded Gels4Bac project aim to develop a novel antibacterial treatment based on their previous discovery that, upon contact with culture media from pathogens, bacteria produce potent antimicrobial vesicles. The objective is to incorporate these vesicles into hydrogels responsive to pathogenic factors for selective and local release in the presence of specific pathogens. This novel treatment will limit side effects, creating new options for selectively treating infections.

Host institution

FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN-NUERNBERG
Net EU contribution
€ 1 499 333,00
Address
Schlossplatz 4
91054 Erlangen
Germany

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Region
Bayern Mittelfranken Erlangen, Kreisfreie Stadt
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00

Beneficiaries (2)

FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN-NUERNBERG
Germany
Net EU contribution
€ 1 499 333,00
Address
Schlossplatz 4
91054 Erlangen

See on map

Region
Bayern Mittelfranken Erlangen, Kreisfreie Stadt
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
HELMHOLTZ-ZENTRUM FUR INFEKTIONSFORSCHUNG GMBH

Participation ended

Germany
Net EU contribution
€ 0,00
Address
Inhoffenstrasse 7
38124 Braunschweig
Region
Niedersachsen Braunschweig Braunschweig, Kreisfreie Stadt
Activity type
Research Organisations
Other funding
€ 0,00