A closer look at mechanisms of epithelial tissue cancers
Chronic gastric infection related to helicobacter pylori is an example of how chronic bacterial infection can induce human cancers of epithelial tissue. Despite its frequent occurrence, the exact mechanisms of microbe-induced epithelial cancer remain unexplained. However, recent research suggests that the precancerous phase of gastric intestinal metaplasia (GIM) could be a form of an organism’s antimicrobial adaptive defence. The EU-funded MADMICS project will investigate this hypothesis to bring new light to the role of bacterial infections in human cancer development. The project will also look at mutational and epigenetic changes connected to GIM as well as a new means of cancer prevention.
Fields of science
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