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A multidisciplinary training network for the bioinspired development of glycomimetics tuning the Siglec-Sialoglycan axis

Objective

GLYTUNES is a multidisciplinary European Training Network on glyco-immune checkpoints built to address the main priorities of the National and European research council regarding the use of innovative methodological, interdisciplinary approaches for the treatment of human diseases. The GLYTUNES program is based on high-level multidisciplinary and multisectoral training to i) understand at the molecular and dynamic level how (aberrant) interactions between the immunomodulatory receptors Siglecs and their sialylated cognate ligands contribute to the etiology of immune-related diseases (infectious, and cancer diseases), ii) how to tune this axis to provide new therapeutic approaches for the rational design and development of glycomimetics targeting the Siglec glyco-immune checkpoints.
To achieve this aim, an interdisciplinary, intersectoral, international European-based training programme within an outstanding collaborative research environment has been established, guided by leaders in their respective fields of research and in close association with industrial partners. GLYTUNES involves 7 academic partners and 4 companies (SMEs) from 7 European countries, combining world-class expertise in carbohydrate chemical and structural biology, drug design and computational chemistry, synthetic and medicinal chemistry, biophysics, biochemistry, glycoimmunology and molecular and medical microbiology. GLYTUNES will train 14 Early Stage Researchers (ESRs) in a highly integrated and collaborative environment, underpinned by extensive interactions between academic and industrial partners and by their experience in higher education, training and mentoring, and endowed with state-of-the art scientific and technical expertise and infrastructures. The ESRs will thus acquire scientific and transferable skills to make them highly competitive and new leaders in top EU academia and research institutions, healthcare and biotech job markets.

Call for proposal

H2020-MSCA-ITN-2020
See other projects for this call

Funding Scheme

MSCA-ITN-ETN - European Training Networks

Coordinator

UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II
Address
Corso Umberto I, 40
80138 Napoli
Italy
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 522 999,36

Participants (10)

QUADRAM INSTITUTE BIOSCIENCE
United Kingdom
EU contribution
€ 303 172,56
Address
Quadram Institute Bioscience Norwich Research Park
NR4 7UQ Norwich
Activity type
Research Organisations
ASOCIACION CENTRO DE INVESTIGACION COOPERATIVA EN BIOCIENCIAS
Spain
EU contribution
€ 250 904,88
Address
Parque Tecnologico Edificio 801 A
48160 Derio Vizcaya
Activity type
Research Organisations
STICHTING VUMC
Netherlands
EU contribution
€ 531 239,76
Address
De Boelelaan 1117
1081 HV Amsterdam
Activity type
Research Organisations
UNIVERSITA DEGLI STUDI DI FIRENZE
Italy
EU contribution
€ 261 499,68
Address
Piazza San Marco 4
50121 Florence
Activity type
Higher or Secondary Education Establishments
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
France
EU contribution
€ 274 802,04
Address
Rue Michel Ange 3
75794 Paris
Activity type
Other
STICHTING KATHOLIEKE UNIVERSITEIT
Netherlands
EU contribution
€ 531 239,76
Address
Houtlaan 4
6525 XZ Nijmegen
Activity type
Higher or Secondary Education Establishments
ATLAS MOLECULAR PHARMA SL
Spain
EU contribution
€ 250 904,88
Address
Bizkaiko Teknologi Elkartegia 800
48160 Derio
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
ICENI DIAGNOSTICS LIMITED
United Kingdom
EU contribution
€ 303 172,56
Address
Nrp Innovation Centre Colney Lane
NR4 7GJ Norwich
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
GLYCOUNIVERSE GMBH & CO. KOMMANDITGESELLSCHAFT AUF AKTIEN
Germany
EU contribution
€ 252 788,40
Address
Am Muhlenberg 11
14476 Potsdam
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
GIOTTO BIOTECH SRL
Italy
EU contribution
€ 261 499,68
Address
Via Madonna Del Piano 6
50019 Sesto Fiorentino Fi
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)