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"ECaBox ""Eyes in a Care Box"": Regenerating human retina from resuscitated cadaveric eyes"

Project description

A closer look at how to resuscitate the human cadaveric eye

Many new drugs and regenerative therapies have been developed in the last decades. But not all translational research is successful. Preclinical research still lacks sufficient models of human organs. The EU-funded ECaBox project will develop a pioneering platform to challenge existing paradigms of testing the efficacy and safety of regenerative therapies ex vivo. The technology intends to resuscitate the human cadaveric eye and guarantee retina function and structure ex vivo for an extended time period. The project will avoid ethical restrictions of human experimentation and serve as a point of contact for therapies in other organs preserved ex vivo. ECaBox will also explore the potential of this innovative technology for tackling retina degeneration causing blindness.

Call for proposal

H2020-FETOPEN-2018-2020

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Sub call

H2020-FETOPEN-2018-2019-2020-01

Coordinator

FUNDACIO CENTRE DE REGULACIO GENOMICA
Net EU contribution
€ 1 142 771,25
Address
Carrer Doctor Aiguader 88
08003 Barcelona
Spain

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Region
Este Cataluña Barcelona
Activity type
Research Organisations
Other funding
€ 0,00

Participants (6)

UNIVERSITAT DE BARCELONA
Spain
Net EU contribution
€ 301 667,50
Address
Gran Via De Les Corts Catalanes 585
08007 Barcelona

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Region
Este Cataluña Barcelona
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
FUNDACIO INSTITUT DE BIOENGINYERIA DE CATALUNYA
Spain
Net EU contribution
€ 232 960,00
Address
Carrer Baldiri Reixac Planta 2a 10-12
08028 Barcelona

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Region
Este Cataluña Barcelona
Activity type
Research Organisations
Other funding
€ 0,00
BAR ILAN UNIVERSITY
Israel
Net EU contribution
€ 355 125,00
Address
Bar Ilan University Campus
52900 Ramat Gan

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Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
ASSOCIATION FOR THE ADVANCEMENT OF TISSUE ENGINEERING AND CELL BASED TECHNOLOGIES & THERAPIES
Portugal
Net EU contribution
€ 520 148,75
Address
Avepark Parque De Ciencia E Tecnologia Zona Zona Industrial Da Gandra S Claudio Do Barco
4805-017 Caldas Das Taipas Caldelas

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Region
Continente Norte Ave
Activity type
Research Organisations
Other funding
€ 0,00
AFERETICA SRL
Italy
Net EU contribution
€ 557 187,50
Address
Via Spartaco 10
40138 Bologna

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Nord-Est Emilia-Romagna Bologna
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
KING'S COLLEGE LONDON
United Kingdom
Net EU contribution
€ 442 283,75
Address
Strand
WC2R 2LS London

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Region
London Inner London — West Westminster
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00