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Toward Precision Toxicology: New Approach Methodologies for Chemical Safety

Project description

Chemical safety assessment without animal testing

The EU aims to promote alternative methods to animal testing. EU-funded PrecisionTox proposes 'precision toxicology', a novel scientific approach establishing causation between chemicals and their adverse health effects. The project focuses on human cell lines and a diverse suite of biomedical model organisms, i.e. fruit flies, water fleas, round worms and embryos of zebrafish and frogs, which share many genes with humans by evolution. These 3Rs compliant, cost-effective testing models enable the mapping of origins of toxicity pathways on the branches of the animal evolutionary tree to predict health risks to humans. By providing data where the toxicity of substances is unknown, PrecisionTox will ultimately translate into regulatory and industrial practices that better protect human health and the environment.

Call for proposal

H2020-SC1-BHC-2018-2020

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Sub call

H2020-SC1-2020-Single-Stage-RTD

Coordinator

THE UNIVERSITY OF BIRMINGHAM
Net EU contribution
€ 5 146 897,50
Address
Edgbaston
B15 2TT Birmingham
United Kingdom

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Region
West Midlands (England) West Midlands Birmingham
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00

Participants (14)

RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG
Germany
Net EU contribution
€ 1 174 990,00
Address
Seminarstrasse 2
69117 Heidelberg

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Region
Baden-Württemberg Karlsruhe Heidelberg, Stadtkreis
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
THE TRUSTEES OF INDIANA UNIVERSITY
United States
Net EU contribution
€ 1 230 916,25
Address
Po Box 1847
47402 Bloomington

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Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
KARLSRUHER INSTITUT FUER TECHNOLOGIE
Germany
Net EU contribution
€ 1 070 220,00
Address
Kaiserstrasse 12
76131 Karlsruhe

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Region
Baden-Württemberg Karlsruhe Karlsruhe, Stadtkreis
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
FUNDACIO CENTRE DE REGULACIO GENOMICA
Spain
Net EU contribution
€ 1 078 483,75
Address
Carrer Doctor Aiguader 88
08003 Barcelona

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Region
Este Cataluña Barcelona
Activity type
Research Organisations
Non-EU contribution
€ 0,00
WATCHFROG
France
Net EU contribution
€ 449 602,50
Address
4 Rue Pierre Fontaine
91000 Evry

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Ile-de-France Ile-de-France Essonne
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
Clemson University Research Foundation
United States
Net EU contribution
€ 998 936,25
Address
Brackett Hall 300
29634 Clemson

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Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
United Kingdom
Net EU contribution
€ 931 793,75
Address
Wellington Square University Offices
OX1 2JD Oxford

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Region
South East (England) Berkshire, Buckinghamshire and Oxfordshire Oxfordshire
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
HELMHOLTZ-ZENTRUM FUR UMWELTFORSCHUNG GMBH - UFZ
Germany
Net EU contribution
€ 972 151,25
Address
Permoserstrasse 15
04318 Leipzig

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Region
Sachsen Leipzig Leipzig
Activity type
Research Organisations
Non-EU contribution
€ 0,00
ALTERTOX
Belgium
Net EU contribution
€ 992 812,50
Address
Alphonse De Witte 11
1050 Ixelles

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Région de Bruxelles-Capitale/Brussels Hoofdstedelijk Gewest Région de Bruxelles-Capitale/ Brussels Hoofdstedelijk Gewest Arr. de Bruxelles-Capitale/Arr. Brussel-Hoofdstad
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
CELL NETWORKS GMBH
Germany
Net EU contribution
€ 1 168 518,75
Address
Lutherstrasse 59
69120 Heidelberg

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Baden-Württemberg Karlsruhe Heidelberg, Stadtkreis
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
MICHABO HEALTH SCIENCE LTD
United Kingdom
Net EU contribution
€ 810 823,75
Address
Union House 111 New Union Street
CV12NT Coventry

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
West Midlands (England) West Midlands Coventry
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
ACONDICIONAMIENTO TARRASENSE ASSOCIACION
Spain
Net EU contribution
€ 568 591,25
Address
Carrer De La Innovacio 2
08225 Terrassa

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Region
Este Cataluña Barcelona
Activity type
Research Organisations
Non-EU contribution
€ 0,00
MISVIK BIOLOGY OY
Finland
Net EU contribution
€ 919 018,75
Address
Karjakatu 35 B
20520 Turku

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Manner-Suomi Etelä-Suomi Varsinais-Suomi
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
LATVIA MGI TECH SIA
Latvia
Net EU contribution
€ 1 791 827,50
Address
Dzirnavu Iela 57A - 4
1010 Riga

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Latvija Latvija Rīga
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00