Skip to main content

Toward Precision Toxicology: New Approach Methodologies for Chemical Safety

Project description

Chemical safety assessment without animal testing

The EU aims to promote alternative methods to animal testing. EU-funded PrecisionTox proposes 'precision toxicology', a novel scientific approach establishing causation between chemicals and their adverse health effects. The project focuses on human cell lines and a diverse suite of biomedical model organisms, i.e. fruit flies, water fleas, round worms and embryos of zebrafish and frogs, which share many genes with humans by evolution. These 3Rs compliant, cost-effective testing models enable the mapping of origins of toxicity pathways on the branches of the animal evolutionary tree to predict health risks to humans. By providing data where the toxicity of substances is unknown, PrecisionTox will ultimately translate into regulatory and industrial practices that better protect human health and the environment.

Call for proposal

H2020-SC1-2020-Single-Stage-RTD
See other projects for this call

Funding Scheme

RIA - Research and Innovation action

Coordinator

THE UNIVERSITY OF BIRMINGHAM
Address
Edgbaston
B15 2TT Birmingham
United Kingdom
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 5 146 897,50

Participants (14)

RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG
Germany
EU contribution
€ 1 174 990
Address
Seminarstrasse 2
69117 Heidelberg
Activity type
Higher or Secondary Education Establishments
THE TRUSTEES OF INDIANA UNIVERSITY
United States
EU contribution
€ 1 230 916,25
Address
Po Box 1847
47402 Bloomington
Activity type
Higher or Secondary Education Establishments
KARLSRUHER INSTITUT FUER TECHNOLOGIE
Germany
EU contribution
€ 1 070 220
Address
Kaiserstrasse 12
76131 Karlsruhe
Activity type
Higher or Secondary Education Establishments
FUNDACIO CENTRE DE REGULACIO GENOMICA
Spain
EU contribution
€ 1 078 483,75
Address
Carrer Doctor Aiguader 88
08003 Barcelona
Activity type
Research Organisations
WATCHFROG
France
EU contribution
€ 449 602,50
Address
4 Rue Pierre Fontaine
91000 Evry
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Clemson University Research Foundation
United States
EU contribution
€ 998 936,25
Address
Brackett Hall 300
29634 Clemson
Activity type
Higher or Secondary Education Establishments
THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
United Kingdom
EU contribution
€ 931 793,75
Address
Wellington Square University Offices
OX1 2JD Oxford
Activity type
Higher or Secondary Education Establishments
HELMHOLTZ-ZENTRUM FUR UMWELTFORSCHUNG GMBH - UFZ
Germany
EU contribution
€ 972 151,25
Address
Permoserstrasse 15
04318 Leipzig
Activity type
Other
ALTERTOX
Belgium
EU contribution
€ 992 812,50
Address
Avenue Du General De Gaulle 36
1050 Ixelles
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
CELL NETWORKS GMBH
Germany
EU contribution
€ 1 168 518,75
Address
Lutherstrasse 59
69120 Heidelberg
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
MICHABO HEALTH SCIENCE LTD
United Kingdom
EU contribution
€ 810 823,75
Address
Union House 111 New Union Street
CV12NT Coventry
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
ACONDICIONAMIENTO TARRASENSE ASSOCIACION
Spain
EU contribution
€ 568 591,25
Address
Carrer De La Innovacio 2
08225 Terrassa
Activity type
Research Organisations
MISVIK BIOLOGY OY
Finland
EU contribution
€ 919 018,75
Address
Karjakatu 35 B
20520 Turku
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
LATVIA MGI TECH SIA
Latvia
EU contribution
€ 1 791 827,50
Address
Dzirnavu Iela 57A - 4
1010 Riga
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)