Investigating the regulatory landscape of neuronal cell specialisation and evolution
Neuronal cells are characterised by a high degree of specialisation, which is necessary for complex brain functions. However, the regulatory mechanisms responsible for neuronal specification and evolution remain largely unknown. The EU-funded NEUROCODE project aims to study the landscape of transcription factors in different types of neuronal cells and how they cooperate to activate gene expression and drive neuron differentiation and specification. For this purpose, scientists will employ the nematode Caenorhabditis elegans as a model organism and single-cell technologies to unravel the regulatory mechanisms responsible for the evolution of neuronal cells. Results will provide fundamental information on brain development and function.
Fields of science
Call for proposal
See other projects for this call