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GUT VIrus BRain Axis Technology In OrgaNoid Science

Project description

Complex organ-on-a-chip system for biomedical research

Organoid technology has achieved a breakthrough in biomedicine, with high potential for viral pathogenesis and antiviral research. The EU-funded GUTVIBRATIONS project will combine expertise in microfabrication, organoid technology, virology, immunology, and bioengineering to create an organ-on-a-chip system as a modular human gut-brain axis multi-organ model. This system will be built by combining 3D-printed scaffold technology with human gut and brain organoids. It will include a gut epithelial layer, immune cells, a blood-brain barrier and a brain organoid, connected by vertical stacking. The extracellular matrix (ECM) scaffold called Biosilk, a recombinant spider silk protein, will result in an in vivo like microenvironmental niche. The project aims to assess the system's commercialisation by a market analysis and a business plan.

Call for proposal

H2020-NMBP-TR-IND-2018-2020

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Sub call

H2020-NMBP-TR-IND-2020-twostage

Coordinator

ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM
Net EU contribution
€ 2 187 375,00
Address
Meibergdreef 15
1105AZ Amsterdam
Netherlands

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Region
West-Nederland Noord-Holland Groot-Amsterdam
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
No data

Participants (6)

DANMARKS TEKNISKE UNIVERSITET
Denmark
Net EU contribution
€ 971 250,00
Address
Anker Engelundsvej 1 Bygning 101 A
2800 Kgs Lyngby

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Region
Danmark Hovedstaden Københavns omegn
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
No data
KATHOLIEKE UNIVERSITEIT LEUVEN
Belgium
Net EU contribution
€ 514 000,00
Address
Oude Markt 13
3000 Leuven

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Region
Vlaams Gewest Prov. Vlaams-Brabant Arr. Leuven
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
No data
UNIQURE BIOPHARMA BV
Netherlands
Net EU contribution
€ 453 750,00
Address
Paasheuvelweg 25
1105BP Amsterdam

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Region
West-Nederland Noord-Holland Groot-Amsterdam
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
No data
BIOLAMINA AB
Sweden
Net EU contribution
€ 377 500,00
Address
Lofstroms Alle 5A
172 66 Sundbyberg

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Östra Sverige Stockholm Stockholms län
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
No data
STEMCELL TECHNOLOGIES UK LTD
United Kingdom
Net EU contribution
€ 967 500,00
Address
Building 7100 Cambridgde Research Park Beach Drive Waterbeach
CB25 9TL Cambridge

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
East of England East Anglia Cambridgeshire CC
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
No data
KUNGLIGA TEKNISKA HOEGSKOLAN
Sweden
Net EU contribution
€ 590 000,00
Address
Brinellvagen 8
100 44 Stockholm

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Region
Östra Sverige Stockholm Stockholms län
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
No data