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Nano bubbles: how, when and why does science fail to correct itself?

Objective

Science relies on the correction of errors to advance, yet in practice scientists find it difficult to erase erroneous and exaggerated claims from the scientific record. Recent discussion of a “replication crisis” has impaired trust in science both among scientists and non-scientists; yet we know little about how non-replicated or even fraudulent claims can be removed from the scientific record. This project combines approaches from the natural, engineering, and social sciences and the humanities (Science and Technology Studies) to understand how error correction in science works and what obstacles it faces, and stages events for scientists to reflect on error and overpromising.

The project’s focus is nanobiology, a highly interdisciplinary field founded around the year 2000 that has already seen multiple episodes of overpromising and promotion of erroneous claims. We examine three such “bubbles”: the claim that nanoparticles can cross the blood-brain barrier; that nanoparticles can penetrate the cell membrane; and the promotion of the “protein corona” concept to describe ordinary adsorption of proteins on nanoparticles. Findings based on error (non)correction in nanobiology should be generalizable to other new, highly interdisciplinary fields such as synthetic biology and artificial intelligence.

We trace claims and corrections in various channels of scientific communication (journals, social media, advertisements, conference programs, etc.) via innovative digital methods. We examine error (non)correction practices in scientific conferences via ethnographic participant-observation. We follow the history of conferences, journals, and other sites of error (non)correction from the 1970s (before nanobio per se existed) to the present. And we attempt to replicate nanobiological claims and, in case of non-replication, document obstacles to correcting those claims. Finally, we will spark a dialogue within the nanobiology community by organizing workshops and events at c

Call for proposal

ERC-2020-SyG
See other projects for this call

Host institution

UNIVERSITE PARIS 13
Address
Avenue Jean-baptiste Clement 99
93430 Villetaneuse
France
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 1 863 947,50

Beneficiaries (7)

UNIVERSITE PARIS 13
France
EU contribution
€ 1 863 947,50
Address
Avenue Jean-baptiste Clement 99
93430 Villetaneuse
Activity type
Higher or Secondary Education Establishments
UNIVERSITEIT MAASTRICHT
Netherlands
EU contribution
€ 1 333 506
Address
Minderbroedersberg 4
6200 MD Maastricht
Activity type
Higher or Secondary Education Establishments
UNIVERSITE GRENOBLE ALPES
France
EU contribution
€ 1 986 167,50
Address
621 Avenue Centrale
38058 Grenoble
Activity type
Higher or Secondary Education Establishments
STICHTING RADBOUD UNIVERSITEIT
Netherlands
EU contribution
€ 1 936 475
Address
Houtlaan 4
6525 XZ Nijmegen
Activity type
Higher or Secondary Education Establishments
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
France
EU contribution
€ 749 250
Address
Rue Michel -Ange 3
75794 Paris
Activity type
Research Organisations
UNIVERSITEIT TWENTE
Netherlands
EU contribution
€ 303 218,75
Address
Drienerlolaan 5
7522 NB Enschede
Activity type
Higher or Secondary Education Establishments
ECOLE NATIONALE DES PONTS ET CHAUSSEES
France
EU contribution
€ 152 896,25
Address
Avenue Blaise Pascal-cite Descartes-champs-sur-marne 6-8
77455 Marne La Vallee Cedex 2
Activity type
Higher or Secondary Education Establishments