Understanding and manipulating the dysregulation of interneurons in schizophrenia

Project description

Mechanistic insight into schizophrenia development

Schizophrenia is a serious mental illness associated with psychosis and distorted perception of reality. Although patients present with increased dopamine levels before psychosis and suspected abnormal activity of midbrain dopamine neurons, the precise mechanisms remain elusive. The EU-funded SchizoFree project aims to shed light on the aetiology of dopamine neuron dysregulation in schizophrenia. Using a mouse model of the disease, researchers will investigate the role of cortical and striatal interneurons in the development of schizophrenia. They hope to identify biomarkers for prompt disease diagnosis and design novel treatments that alleviate schizophrenia symptoms.

Fields of science

• medical and health sciences › clinical medicine › psychiatry › schizophrenia

Programme(s)

• H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions Main Programme
• H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility

Topic(s)

• MSCA-IF-2020 - Individual Fellowships

Call for proposal

H2020-MSCA-IF-2020

See other projects for this call

Funding Scheme

MSCA-IF - Marie Skłodowska-Curie Individual Fellowships (IF)

Coordinator

KING'S COLLEGE LONDON

Net EU contribution

€ 212 933,76

Address

Strand
WC2R 2LS London
United Kingdom

Region

London › Inner London — West › Westminster

Activity type

Higher or Secondary Education Establishments

Links

Other funding

€ 0,00