Novel antiviral siRNAs help fight beet virus
Beet yellows virus (BYV) is a highly destructive plant pathogen. The recent EU regulatory ban on the use of neonicotinoid pesticides means a new approach is urgently needed to combat virus yellows disease. One answer is small molecular inhibitors called 'artificial small interfering RNAs' (art-siRNAs) that specifically bind to and deactivate BYVs within the plants. The EU-funded ultraRNAs project will design and assess structure-based art-siRNAs (ultraRNAs) within laboratories, glasshouses and in-field. The aim is for the art-siRNAs to be applied to sugar beet seed pellets and be taken up by the seedlings as they grow. When BYV infects the treated plants, the art-siRNAs will bind to the BYV RNA strands and deactivate them, thereby preventing disease.
Fields of science
Funding SchemeERC-POC-LS - ERC Proof of Concept Lump Sum Pilot
NR4 7UH Norwich
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