Project description
Preventing cell-to-cell viral spread in plants
Viruses cause epidemics on all major crops and thus represent a serious threat to global agriculture and food security. Plant viruses can exploit plasmodesmata, channels that interconnect every single plant cell, using encoded so-called movement proteins (MPs) that mediate the transport of the viral genomes cell-to-cell. Understanding the intercellular transport of viruses and the components involved offers breeding targets for genome editing to control virus spread and block viral infection. The EU-funded PDgate project will identity MP-interacting proteins using high-end proteomics and apply state-of-the-art technology genome editing and advanced microscopy to define the role of MP-interacting proteins during virus transport and infection, laying the basis for novel biotech solutions in agriculture.
Fields of science
- medical and health sciencesmedical biotechnologygenetic engineeringgene therapy
- natural sciencesbiological sciencesmicrobiologyvirology
- natural sciencesbiological sciencesgeneticsgenomesviral genomes
- medical and health scienceshealth sciencesnutrition
- agricultural sciencesagriculture, forestry, and fisheriesagriculture
Programme(s)
Funding Scheme
MSCA-IF-EF-ST - Standard EFCoordinator
40225 Dusseldorf
Germany
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