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Investigating human neuronal transplantation integration and interaction at the single cell level

Project description

Investigation of neuronal transplantation at the individual cell level

Neuronal death is a contributing factor to the neuronal loss in chronic neurodegeneration and dementia, such as amyotrophic lateral sclerosis and Alzheimer’s disease, and also in cases of cerebral ischemia and traumatic brain injury. Attempts to replace the lost neurons by transplantation look promising and attractive from a medical perspective but require a significantly better understanding of transplants’ integration and interaction with the host environment. Funded by the Marie Skłodowska Curie Actions programme, the NeurTransHet project will employ single-cell transcriptomics technology and high-resolution imaging to investigate the individual cell contribution, the effect of transplant heterogeneity, and the interaction of the transplanted cells with the environment in a mouse model of human neuronal transplantation.


Net EU contribution
€ 162 806,40
Geschwister Scholl Platz 1
80539 Muenchen

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Bayern Oberbayern München, Kreisfreie Stadt
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00