It’s all about timing: the paradigm of embryonic development
Embryonic development begins after fertilisation and undergoes the same stages in many species, at however different paces depending on the organism. The underlying aetiology of the differences in developmental time between species remains unclear. The working hypothesis of the EU-funded ALLOCHRONY project is that this developmental allochrony is due to different rates in key biochemical reactions. Researchers will develop organoids from pluripotent stem cells that mimic early embryogenesis to study key reactions in mouse and human cells. Results will advance existing knowledge on embryonic development and identify the rate-limiting steps in the process.
Fields of science
Funding SchemeERC-COG - Consolidator Grant
See on map