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Constructing chiral molecules merging ELECTRochemistry and ORGANOcatalysis

Project description

Combining electrochemistry and organocatalysis to provide chiral molecules for the pharmaceutical industry

Drug discovery identifies successful candidate therapeutics, and catalytic methods for the production of chiral molecules, which are non-superposable on their mirror image, are extremely valuable. Funded by the Marie Skłodowska-Curie Actions programme, the ELECTRORGANO project aims to combine asymmetric organocatalysis and microfluidic electrochemistry as modes of molecule activation for the formation of chiral molecules. The objective is to use an electrochemical microfluidic setup coupled with asymmetric organocatalysis to overcome intrinsic technological limitations, creating chiral building blocks with high stereocontrol. Additionally, mechanistic studies aim to provide a fundamental understanding of enantioselective induction, setting the stage for future breakthroughs in enantioselective electrochemistry.

Coordinator

UNIVERSITEIT VAN AMSTERDAM
Net EU contribution
€ 175 572,48
Address
Spui 21
1012WX Amsterdam
Netherlands

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Region
West-Nederland Noord-Holland Groot-Amsterdam
Activity type
Higher or Secondary Education Establishments
Other funding
€ 175 572,48