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Engineering the mitral valve: bioinspired control of structure and function for enhanced in vivo performance

Project description

Tissue-engineered heart valves

The mitral valve is responsible for maintaining proper blood flow in the heart in one direction, from the left atrium to the left ventricle. When the mitral valve doesn’t work properly, the heart does not pump enough blood, causing fatigue and shortness of breath. In severe cases, prosthetic heart valves are used to replace dysfunctional valves. The EU-funded BIOMITRAL project will focus on tissue engineered valves that have the capacity to also regenerate the endogenous tissue, facilitate remodelling, and grow with the patient. Researchers will develop a polymer-based mitral valve that functions according to the native physiological mechanism and exhibits enhanced functional performance.

Host institution

FONDAZIONE RI.MED
Net EU contribution
€ 1 880 506,25
Address
Via Bandiera 11
90133 Palermo
Italy

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Region
Isole Sicilia Palermo
Activity type
Research Organisations
Other funding
€ 0,00

Beneficiaries (3)

FONDAZIONE RI.MED
Italy
Net EU contribution
€ 1 880 506,25
Address
Via Bandiera 11
90133 Palermo

See on map

Region
Isole Sicilia Palermo
Activity type
Research Organisations
Other funding
€ 0,00
ISTITUTO MEDITERRANEO PER I TRAPIANTI E TERAPIE AD ALTA SPECIALIZZAZIONE SRL - ISMETT SRL
Italy
Net EU contribution
€ 91 250,00
Other funding
€ 0,00
UNIVERSITA DEGLI STUDI DI PALERMO
Italy
Net EU contribution
€ 18 773,75
Address
Piazza Marina 61
90133 Palermo

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Region
Isole Sicilia Palermo
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00