Solving the mystery of mitochondrial respiration
Mitochondria are considered the powerhouse of eukaryotic cells, facilitating the production of most of the required energy in the form of ATP. Enzymes of the respiratory chain are responsible for converting the energy released from catabolic processes within the cell to ATP. The EU-funded RESPICHAIN project will focus on complex I, the largest respiratory enzyme that consists of 45 subunits. Researchers will investigate the mechanism of energy transduction carried out by complex I and delineate its structure. The work will provide fundamental knowledge in biology and insight into the aetiology of many human diseases.
Fields of science
Funding SchemeERC-ADG - Advanced Grant
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