Using bioprinted tissue to prevent osteoarthritis
Musculoskeletal disorders like osteoarthritis – a degenerative condition affecting millions of people worldwide – are the most common causes of chronic pain, disability and morbidity. Current treatments are limited in their efficacy. While musculoskeletal regeneration has become a prominent research area, regenerative strategies have failed so far to produce tissues mimicking the exquisite structural complexity of native tissues, dramatically limiting their clinical utility. In this context, the EU-funded 4D-BOUNDARIES project will use 3D bioprinting technologies to engineer, for the first time, patient-specific cartilage and meniscal grafts that mimic the internal and external anatomy and anisotropic mechanical properties of the native tissues. In the case of osteoarthritis, the ability to bioprint such functional tissues could prevent its development.
Fields of science
Funding SchemeERC-ADG - Advanced Grant
D02 CX56 Dublin 2
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